Protein Alignment CG18735 and TMPRSS11A

DIOPT Version :10

• Sequence 1: NP_652645.1
• Gene: CG18735 / 59137
• FlyBaseID: FBgn0042098
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: NP_872412.3
• Gene: TMPRSS11A / 339967
• HGNCID: 27954
• Length: 421
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 94/293 - (32%)
• Similarity: 142/293 - (48%)
• Gaps: 38/293 - (12%)

  Fly    49 IQSILGPEV------PAE--------WSSPAKRECAECSCG------NINTRHRIVGGQETEVHE 93
            |||||..::      |..        .||.......:.|||      |:|   ||..|.......
Human   139 IQSILNQKIRNLRALPINASSVQVNAMSSSTGELTVQASCGKRVVPLNVN---RIASGVIAPKAA 200

  Fly    94 YPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGFYHRLITVRLLEHNRQDS-----HVKIVDRR 153
            :||...|.:.....|||:|:::.:.:|||||...:.:        .|....|     :..::.|.
Human   201 WPWQASLQYDNIHQCGATLISNTWLVTAAHCFQKYKN--------PHQWTVSFGTKINPPLMKRN 257

  Fly   154 VSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENYAGQTAV-VTGWGALSEGGP 217
            |.|.:||.||.:...:.|||:::.:..|....|:..:|:|..|.::.....| :||:|||..||.
Human   258 VRRFIIHEKYRSAAREYDIAVVQVSSRVTFSDDIRQICLPEASASFQPNLTVHITGFGALYYGGE 322

  Fly   218 ISDTLQEVEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQL 282
            ..:.|:|..|.|:|.:.|:......:.|...|.||||:| |..|:|:||||||:......|.:.|
Human   323 SQNDLREARVKIISDDVCKQPQVYGNDIKPGMFCAGYME-GIYDACRGDSGGPLVTRDLKDTWYL 386

  Fly   283 AGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENT 315
            .||||||:.|.:.:.|||||:|..:.:|||..|
Human   387 IGIVSWGDNCGQKDKPGVYTQVTYYRNWIASKT 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	79/236 (33%)
TMPRSS11A	NP_872412.3	SEA	49..149	CDD:460188	5/9 (56%)
		Tryp_SPc	190..418	CDD:238113	79/236 (33%)