DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and plg

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_958880.2	Gene:	plg / 322691	ZFINID:	ZDB-GENE-030131-1411	Length:	818	Species:	Danio rerio

Alignment Length:	289	Identity:	93/289 - (32%)
Similarity:	148/289 - (51%)	Gaps:	45/289 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 EVPAEW---SSPAKR-------ECAECSCGNINTR-----HRIVGGQETEVHEYPWMIMLMWFGN 105
            :|...|   :.|:|:       :|....||...|:     .|||||..::.|.:||.|.|...|.
Zfish   547 DVNGPWCYTTDPSKKWDYCQIPDCESLKCGQPATKPKRCFGRIVGGCVSKPHSWPWQISLRTRGK 611

  Fly   106 F-YCGASLVNDQYALTAAHCVN-----GFYHRLI---TVRLLEHNRQDSHVKIVDRRVSRVLIHP 161
            . :||.:|::.|:.:|||||:.     ..|..::   |.|..|.::|       :|.|::::..|
Zfish   612 IHFCGGTLIDPQWVVTAAHCLERSDSPSAYKIMLGIHTERATESSKQ-------ERDVTKIIKGP 669

  Fly   162 KYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENY---AGQTAVVTGWGALSEGGPISDTLQ 223
            .      .:||||::.:.|..:...:.|||:  |.::|   :.....|||||...:.|. ...|:
Zfish   670 A------GTDIALLKLDRPALINDKVSPVCL--PEKDYIVPSNTECYVTGWGETQDTGG-EGYLK 725

  Fly   224 EVEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSW 288
            |...|::..:.|...::...::.|:.:|||.:| ||.||||||||||: |..:.:.:.|.|:.||
Zfish   726 ETGFPVIENKVCNRPSFLNGRVKDHEMCAGNIE-GGNDSCQGDSGGPL-VCYAQNTFVLQGVTSW 788

  Fly   289 GEGCAKPNAPGVYTRVGSFNDWIAENTRD 317
            |.|||....|||||||..|.|||..:.::
Zfish   789 GLGCANAMKPGVYTRVSKFVDWIERSIKE 817

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	83/240 (35%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	84/242 (35%)
plg	NP_958880.2	PAN_AP_HGF	31..104	CDD:238532
		KR	109..190	CDD:214527
		KR	190..270	CDD:214527
		KR	281..361	CDD:214527
		Kringle	376..453	CDD:306546
		KR	490..572	CDD:214527	5/24 (21%)
		Tryp_SPc	589..813	CDD:238113	84/241 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910