DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and Tmprss11b

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_795998.2	Gene:	Tmprss11b / 319875	MGIID:	2442893	Length:	416	Species:	Mus musculus

Alignment Length:	300	Identity:	102/300 - (34%)
Similarity:	139/300 - (46%)	Gaps:	55/300 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 SASDPEKILNNLAQLRQSSFLDWIQSILGPEVPAEWSSPAKRECAECSCGNINTRHRIVGGQETE 90
            |..|.|||:||....|             |.:.|                   |..||.||....
Mouse   160 SKVDAEKIINNRCGRR-------------PRMSA-------------------TYDRITGGSTAH 192

  Fly    91 VHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNG---------FYHRLITVRLLEHNRQDSH 146
            ..|:||...|...|..||||||:.:::.||||||..|         .:...:|...::|:
Mouse   193 KGEWPWQASLRVNGKHYCGASLIGERFLLTAAHCFQGTNNPKNLTVSFGTRVTPAYMQHS----- 252

  Fly   147 VKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENY-AGQTAVVTGWG 210
                   |..::||..|.......|:|:|:..|.|....|:|.||:|..::.: .|:..||||||
Mouse   253 -------VQEIIIHEDYVKGEHHDDVAVIKLTEKVSFNNDVHRVCLPESTQIFPPGEGVVVTGWG 310

  Fly   211 ALSEGGPISDTLQEVEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLG 275
            :.|..|.....||:..:.|:....|.:......:|.|.|:||||:| |..|:||||||||:....
Mouse   311 SFSYNGKSPLLLQKASIKIIDTNTCNSEEAYGGRIVDTMLCAGYLE-GSIDACQGDSGGPLVHPN 374

  Fly   276 SGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENT 315
            |.|.:.|.||||||..|.:.|.||||.||.|:.:|||..|
Mouse   375 SRDIWYLVGIVSWGHECGRVNKPGVYMRVTSYRNWIASKT 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	87/238 (37%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	89/240 (37%)
Tmprss11b	NP_795998.2	SEA	46..140	CDD:279699
		Tryp_SPc	184..410	CDD:214473	87/238 (37%)
		Tryp_SPc	185..413	CDD:238113	89/240 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	179	1.000	Inparanoid score	I3995
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960