DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and C1s2

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_776289.2	Gene:	C1s2 / 317677	MGIID:	3644269	Length:	694	Species:	Mus musculus

Alignment Length:	310	Identity:	98/310 - (31%)
Similarity:	148/310 - (47%)	Gaps:	77/310 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 WIQSILGPEVPAEWSSPAKRECAECSCG----NINTRHRIVGGQETEVHEYPWMIMLMWFGNFYC 108
            |:...||.|:|         .|... ||    ....:.:|.|||..::..:||.:   :|.:...
Mouse   415 WVNDQLGIELP---------RCIPV-CGVPTEPFQVQQKIFGGQPAKIENFPWQV---FFNHPTA 466

  Fly   109 GASLVNDQYALTAAHCVN-----GFYHRLITVRLLE-HNRQDSHVKIVDRRVSRVLIHPKYS--- 164
            |.:|:|:.:.|||||.|.     ..|..:..:||.: .|.|..:.|       ||:|||.:.
Mouse   467 GGALINEYWVLTAAHVVEKNSDPSMYAGITALRLADLENAQRLYTK-------RVIIHPGWKEDD 524

  Fly   165 ----TRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENY---AGQTAVVTGWGALSEGGPISDTL 222
                ..|||:||||::..:||::|....|:|:|..|..|   .|...:::|||...:...:.: |
Mouse   525 DLNPRTNFDNDIALVQLKDPVKMGPKFSPICLPGTSSEYNLSPGDMGLISGWGRTEKRLHVIN-L 588

  Fly   223 QEVEVPILSQEEC----------RNSNYGESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSG 277
            :..:||:.|.|.|          |..:|   .|||||||||   :.|.|||:|||||..
Mouse   589 RGAKVPVTSLETCKQVKEENPTARPEDY---VITDNMICAG---EKGVDSCKGDSGGAF------ 641

  Fly   278 DAYQ----------LAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENTRD 317
             |:|          :||:||||:.|   .|.||||:|.::.|||.:..::
Mouse   642 -AFQVPNVKAPKFYVAGLVSWGKKC---GAYGVYTKVKNYVDWILKTMQE 687

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	88/264 (33%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	90/266 (34%)
C1s2	NP_776289.2	CUB	24..135	CDD:238001
		FXa_inhibition	149..177	CDD:291342
		CUB	181..293	CDD:278839
		CCP	300..361	CDD:153056
		CCP	365..428	CDD:153056	5/21 (24%)
		Tryp_SPc	443..681	CDD:214473	88/264 (33%)
		Tryp_SPc	444..684	CDD:238113	90/266 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910