Protein Alignment CG18735 and HABP2

DIOPT Version :10

• Sequence 1: NP_652645.1
• Gene: CG18735 / 59137
• FlyBaseID: FBgn0042098
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: NP_004123.1
• Gene: HABP2 / 3026
• HGNCID: 4798
• Length: 560
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 53/246 - (21%)
• Similarity: 87/246 - (35%)
• Gaps: 55/246 - (22%)

  Fly   941 FSQDQHGSRFIQQ---KLERAISVEKQLVFNEILGAAYSLMTDVFGNYVI---QKFFEFGSPEQK 999
            |..|:.|..|...   |:.:.|...::....|..|.||..::.:..:..:   :|.|:....|:.
Human   526 FGCDECGKAFRNNSGLKVHKRIHTGERPYKCEECGKAYISLSSLINHKSVHPGEKPFKCDECEKA 590

  Fly  1000 ----QALAQQVKGHVLPLALQMYGCRVIQKALE--SIPAEQQQEIVRELDGHVLKCVKDQNGN-- 1056
                :.|....|.|   |..:.|.|.|.:|:..  |:.::.::...||......:|.|....|
Human   591 FITYRTLLNHKKIH---LGEKPYKCDVCEKSFNYTSLLSQHKRVHTREKPFECDRCEKVFRNNSS 652

  Fly  1057 -------HVVQKCIECVDPVALQFIIDAFRNQVYSLSTH----PYGCRVIQRILEHCTPEQTAPI 1110
                   |..:|..|| |.....:|  :..:.:...|||    ||.|       :.|.....:..
Human   653 LKVHKRIHTGEKPYEC-DICGKAYI--SHSSLINHKSTHPGKTPYTC-------DECGKAFFSSR 707

  Fly  1111 LAELHANTEHLIQDQYGNYVIQHVLEHGKPEDKSALIASVRGKVLILSQHK 1161
            ....|... ||.:..:      ..:|.||....|:|          |||||
Human   708 TLISHKRV-HLGEKPF------KCVECGKSFSYSSL----------LSQHK 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113
HABP2	NP_004123.1	EGF	77..106	CDD:394967
		KR	191..277	CDD:238056
		Tryp_SPc	314..553	CDD:238113	6/26 (23%)