Protein Alignment CG18735 and PRSS50

DIOPT Version :9

• Sequence 1: NP_652645.1
• Gene: CG18735 / 59137
• FlyBaseID: FBgn0042098
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: NP_037402.1
• Gene: PRSS50 / 29122
• HGNCID: 17910
• Length: 385
• Species: Homo sapiens
• Alignment Length: 380
• Identity: 97/380 - (25%)
• Similarity: 152/380 - (40%)
• Gaps: 84/380 - (22%)

  Fly     7 LLILATALGDLAC----ATPSLRSASDPEKILNNLAQLRQSSFLDWIQSILGPEVPAE-----WS 62
            ||:|...|....|    ..|...|.:||..         ||     :|.:.....|:.     |.
Human    25 LLLLLLLLRSAGCWGAGEAPGALSTADPAD---------QS-----VQCVPKATCPSSRPRLLWQ 75

  Fly    63 SPAKRECAEC-----------------SCGNINTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGA 110
            :|..:.....                 |||....:...:...|.....:|||:.:...|...|..
Human    76 TPTTQTLPSTTMETQFPVSEGKVDPYRSCGFSYEQDPTLRDPEAVARRWPWMVSVRANGTHICAG 140

  Fly   111 SLVNDQYALTAAHCVNGFYHRLI-TVRL----LEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDS 170
            :::..|:.||.|||:  .:..:| :||:    ::...|.:.    |..|.:|::|.:|..:.|.|
Human   141 TIIASQWVLTVAHCL--IWRDVIYSVRVGSPWIDQMTQTAS----DVPVLQVIMHSRYRAQRFWS 199

  Fly   171 ------DIALIRFNEPVRLGIDMHPVCMPTPSENYA---GQTAVVTGWGALSEGG--PISDTLQE 224
                  ||.|::..:.::....:.|:|:  |..:|.   .....|||||.....|  |...|:||
Human   200 WVGQANDIGLLKLKQELKYSNYVRPICL--PGTDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQE 262

  Fly   225 VEVPILSQEECRNSNYGESK-------ITDNMICAGYVEQGGKDS-CQGDSGGPMHVLGSGDAYQ 281
            .||.||:.:||.|..:..:|       |...|:||   |...::. |...:|.|: |......:.
Human   263 KEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCA---EDTHREKFCYELTGEPL-VCSMEGTWY 323

  Fly   282 LAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENTRDACSCAQPEAAGEPASPMET 336
            |.|:||||.||.|..||.:|.:|.|:..||.:       |...:|...|| |..|
Human   324 LVGLVSWGAGCQKSEAPPIYLQVSSYQHWIWD-------CLNGQALALPA-PSRT 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	71/252 (28%)
		Tryp_SPc	83..314	CDD:238113	73/254 (29%)
PRSS50	NP_037402.1	Tryp_SPc	118..353	CDD:238113	71/246 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910