DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and F11

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_006253206.1	Gene:	F11 / 290757	RGDID:	1309364	Length:	622	Species:	Rattus norvegicus

Alignment Length:	257	Identity:	91/257 - (35%)
Similarity:	139/257 - (54%)	Gaps:	22/257 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 CSCGNINT---RHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNG------ 127
            |...|:.|   |.|:.||..:...|:||.:.|.......||.|::.:::.||||||.:|
  Rat   374 CKMDNVCTTKIRPRVFGGAASVHGEWPWQVTLHTTQGHLCGGSIIGNRWILTAAHCFSGTETPKT 438

  Fly   128 --FYHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPV 190
              .|..::       |:.:.:......||..::||.:|::.....||||::....:.......|:
  Rat   439 LRVYGGIV-------NQSEINEDTTFFRVQEMIIHDQYTSAESGFDIALLKLEPAMNYTDFQRPI 496

  Fly   191 CMPTPSE-NYAGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNYGESKITDNMICAGY 254
            |:|:..: |.......|||||.......:..|||:.:||::|.|||: :.|.:.|||:.:|||||
  Rat   497 CLPSKGDRNVVHTECWVTGWGYTKSRDEVQSTLQKAKVPLVSNEECQ-TRYRKHKITNKVICAGY 560

  Fly   255 VEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENTR 316
             ::||||:|:||||||:....:| .:.|.||.||||||.:...|||||.|..:.|||.|.|:
  Rat   561 -KEGGKDTCKGDSGGPLSCKHNG-VWHLVGITSWGEGCGQKERPGVYTNVAKYVDWILEKTQ 620

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	83/237 (35%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	84/239 (35%)
F11	XP_006253206.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..374	CDD:128519	91/257 (35%)
		Tryp_SPc	387..615	CDD:214473	83/237 (35%)
		Tryp_SPc	388..615	CDD:238113	82/236 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810