Protein Alignment CG18735 and TMPRSS11E

DIOPT Version :10

• Sequence 1: NP_652645.1
• Gene: CG18735 / 59137
• FlyBaseID: FBgn0042098
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: NP_054777.2
• Gene: TMPRSS11E / 28983
• HGNCID: 24465
• Length: 423
• Species: Homo sapiens
• Alignment Length: 335
• Identity: 114/335 - (34%)
• Similarity: 161/335 - (48%)
• Gaps: 55/335 - (16%)

  Fly     5 HLLLILATALGDLACATPSLRSASDPEKILNNLAQLRQSSFLDWIQSILGPEVPAEWSSPAKR-- 67
            |:|||         |   ...|..|||.: :.:.||   ...:.:|..:||......|...|:
Human   118 HMLLI---------C---RFHSTEDPETV-DKIVQL---VLHEKLQDAVGPPKVDPHSVKIKKIN 166

  Fly    68 ---------ECAECSCGNINTRH-----RIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYA 118
                     .|    ||...::.     |||||.|.|..|:||...|.|.|:..|||:|:|..:.
Human   167 KTETDSYLNHC----CGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWL 227

  Fly   119 LTAAHCVNGFYHRL-------ITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIR 176
            ::||||...:.:..       :|::       .|.:|   |.:.|:::|.||...:.|.||:|..
Human   228 VSAAHCFTTYKNPARWTASFGVTIK-------PSKMK---RGLRRIIVHEKYKHPSHDYDISLAE 282

  Fly   177 FNEPVRLGIDMHPVCMPTPS-ENYAGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNY 240
            .:.||.....:|.||:|..| |...|....|||:|||...|...:.|::.:|.::....|.....
Human   283 LSSPVPYTNAVHRVCLPDASYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQA 347

  Fly   241 GESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVG 305
            ....||..|:|||.:| |..|:||||||||:....:.|.:.||||||||:.|||||.|||||||.
Human   348 YNDAITPRMLCAGSLE-GKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVT 411

  Fly   306 SFNDWIAENT 315
            :..|||...|
Human   412 ALRDWITSKT 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	93/238 (39%)
TMPRSS11E	NP_054777.2	SEA	51..147	CDD:460188	11/44 (25%)
		Tryp_SPc	192..420	CDD:238113	93/238 (39%)