DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and Tmprss7

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_001099352.2	Gene:	Tmprss7 / 288118	RGDID:	1304655	Length:	829	Species:	Rattus norvegicus

Alignment Length:	328	Identity:	110/328 - (33%)
Similarity:	165/328 - (50%)	Gaps:	57/328 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 GDLAC--------------ATPSLRSASDPEKILNNLAQLRQSSFLDWIQSILGPEVPAEWSSPA 65
            |.|.|              .|.|:...:...|..|::...:|::..|.|.           ..|.
  Rat   520 GPLVCDGFQDCEDGQDEQNCTRSIPCTNRTFKCGNDICFRKQNAQCDGIV-----------DCPD 573

  Fly    66 KRECAECSCGNINT-RHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGFY 129
            :.:...|.|...:. .||:|||.:::...:||.:.|.:.|:.:||||:::.::.|:||||.:|
  Rat   574 RSDEEGCGCSRSSPFLHRVVGGSDSQEGTWPWQVSLHFVGSAHCGASVISREWLLSAAHCFHG-- 636

  Fly   130 HRLITVRLLEHNRQDSHV--------KIVDRRVSRVLIHPKYSTRNFDSDIALIRFN--EPVRLG 184
                 .||.:.....:|:        |.|. .|.|:::|..|:::.||.||||::.:  .|..|.
  Rat   637 -----NRLSDPTPWTAHLGMYVQGNAKFVS-PVRRIVVHEYYNSQTFDYDIALLQLSIAWPETLR 695

  Fly   185 IDMHPVCMPTPSENY-AGQTAVVTGWG----ALSEGGPISDTLQEVEVPILSQEECRNSNYGESK 244
            ..:.|:|:|...:.. :|:...|||||    |.|:|.||   ||:.||.::.|..| .|.||  .
  Rat   696 QLIQPICIPPVGQRVRSGEKCWVTGWGRRHEADSKGSPI---LQQAEVELIDQTVC-VSTYG--I 754

  Fly   245 ITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDA-YQLAGIVSWGEGCAKPNAPGVYTRVGSFN 308
            ||..|:||| |..|..|:|:||||||:......|. :.|.||||||.||.:||.|||||||.:|.
  Rat   755 ITSRMLCAG-VMSGKSDACKGDSGGPLSCRRKSDGKWILTGIVSWGYGCGRPNFPGVYTRVSNFV 818

  Fly   309 DWI 311
            .||
  Rat   819 PWI 821

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	94/244 (39%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	95/245 (39%)
Tmprss7	NP_001099352.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	30..49
		SEA	94..190	CDD:279699
		CUB	<257..345	CDD:238001
		LDLa	470..504	CDD:238060
		LDLa	545..580	CDD:238060	6/45 (13%)
		Tryp_SPc	591..821	CDD:214473	94/244 (39%)
		Tryp_SPc	592..823	CDD:238113	95/245 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910