Protein Alignment CG18735 and PRSS33

DIOPT Version :9

• Sequence 1: NP_652645.1
• Gene: CG18735 / 59137
• FlyBaseID: FBgn0042098
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: NP_001372391.1
• Gene: PRSS33 / 260429
• HGNCID: 30405
• Length: 280
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 100/253 - (39%)
• Similarity: 134/253 - (52%)
• Gaps: 19/253 - (7%)

  Fly    73 SCGNINTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGFYHRLI---- 133
            :||......|||||::....|:||...:...|...||.||:..|:.||||||   |..|.:
Human    27 ACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHC---FPRRALPAEY 88

  Fly   134 TVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPTP-SE 197
            .|||.......:..:.:...|.|||:.|.||......|:||::...||.|...:.|||:|.| :.
Human    89 RVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPVCLPVPGAR 153

  Fly   198 NYAGQTAVVTGWGALSEGGPISD--TLQEVEVPILSQEECRNSNY-------GESKITDNMICAG 253
            ...|....|||||:|..|.|:.:  .||.|.||:|....|....:       .|..:....:|||
Human   154 PPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAG 218

  Fly   254 YVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWI 311
            | .||.||:||||||||:..|.|| ::.|.|:||||:|||.||.|||||.|.:::.||
Human   219 Y-PQGHKDACQGDSGGPLTCLQSG-SWVLVGVVSWGKGCALPNRPGVYTSVATYSPWI 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	96/242 (40%)
		Tryp_SPc	83..314	CDD:238113	97/243 (40%)
PRSS33	NP_001372391.1	Tryp_SPc	37..275	CDD:238113	97/243 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4746
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3952
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.790