DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and mst1

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_694512.1	Gene:	mst1 / 259260	ZFINID:	ZDB-GENE-020806-3	Length:	709	Species:	Danio rerio

Alignment Length:	268	Identity:	65/268 - (24%)
Similarity:	120/268 - (44%)	Gaps:	30/268 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 ILGPEVPAEWSSPAKRECAECSCGNINTRHRIVGGQETEVHEYPWMIMLM-WFGNFYCGASLVND 115
            |:||....|::...|||      ..:.:|.|||||..   ...||.:.|. ..||.:||.|||:.
Zfish   457 IIGPTTEVEFNECGKRE------DRLRSRLRIVGGTP---GNSPWTVSLRDRKGNHFCGGSLVSS 512

  Fly   116 QYALTAAHCVNGFYHRL----ITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIR 176
            ::.::...|.:..|..|    ..:..|..:.::....:....:::::..|.      :|.:.:::
Zfish   513 EWVISTKQCFSSCYVDLTGYTAMMGTLFRDPKEGEPDLQRISLTKIVCGPS------ESHLVMLQ 571

  Fly   177 FNEPVRLGIDMHPVCMPTPSENYA---GQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNS 238
            ...|.:....:..:|:  |.|.|.   |....:.|||. ::|......|...::|:||.::|  :
Zfish   572 LETPAQFNERVSQICL--PPERYIVPDGTICEIAGWGE-TKGKGDETVLNVAQMPVLSNKDC--N 631

  Fly   239 NYGESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTR 303
            .|.:.::.:|.:|. ...|.|..:|:.|.|||:....| |.:.|.|::.....|.....|.::.|
Zfish   632 QYFKGRVRENEMCT-MAFQAGVGACERDYGGPLACQNS-DCWVLEGVIIPMRRCGHAGQPNIFIR 694

  Fly   304 VGSFNDWI 311
            |..:.|||
Zfish   695 VSVYVDWI 702

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	55/236 (23%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	56/237 (24%)
mst1	NP_694512.1	PAN_AP_HGF	24..105	CDD:238532
		KR	109..187	CDD:238056
		KR	192..271	CDD:214527
		KR	284..365	CDD:214527
		KR	370..451	CDD:238056
		Tryp_SPc	481..702	CDD:214473	55/236 (23%)
		Tryp_SPc	482..705	CDD:238113	56/237 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910