DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and Proc

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_008770240.3	Gene:	Proc / 25268	RGDID:	3411	Length:	500	Species:	Rattus norvegicus

Alignment Length:	242	Identity:	90/242 - (37%)
Similarity:	134/242 - (55%)	Gaps:	20/242 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 RIVGGQETEVHEYPWM-IMLMWFGNFYCGASLVNDQYALTAAHCVNGFYHRLITVRLLEHNRQDS 145
            |||.|..|:..:.||. |:|.......||..|::..:.||||||:..  .:.:||||.|::.:..
  Rat   251 RIVNGTLTKQGDSPWQAILLDSKKKLACGGVLIHTSWVLTAAHCLES--SKKLTVRLGEYDLRRR 313

  Fly   146 HVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMP----TPSENYAGQTAVV 206
            ....:|..:..||:||.|:..|.|:||||:|.::|..|...:.|:|:|    ....:.|||..||
  Rat   314 DPWELDLDIKEVLVHPNYTRSNSDNDIALLRLSQPATLSKTIVPICLPNSGLAQELSQAGQETVV 378

  Fly   207 TGWGALSEGGPISD-------TLQEVEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDSCQ 264
            ||||..|:  .:.|       .|..:.:|:.::.:|  .....:.:::||:|||.:.. .:|:|.
  Rat   379 TGWGYQSD--KVKDGRRNRTFILTFIRIPLAARNDC--MQVMNNVVSENMLCAGIIGD-TRDACD 438

  Fly   265 GDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWI 311
            |||||||.|...| .:.|.|:|||||||...|..||||:|||:..||
  Rat   439 GDSGGPMVVFFRG-TWFLVGLVSWGEGCGHLNNYGVYTKVGSYLKWI 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	88/240 (37%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	89/241 (37%)
Proc	XP_008770240.3	GLA	65..125	CDD:214503
		EGF_CA	126..170	CDD:238011
		FXa_inhibition	178..213	CDD:405372
		Tryp_SPc	252..486	CDD:238113	89/241 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm12321
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910