DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and Klkb1

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_036857.2	Gene:	Klkb1 / 25048	RGDID:	67382	Length:	638	Species:	Rattus norvegicus

Alignment Length:	263	Identity:	97/263 - (36%)
Similarity:	142/263 - (53%)	Gaps:	25/263 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 ECAECSCGNINTRHRIVGGQETEVHEYPWMIML---MWFGNFYCGASLVNDQYALTAAHCVNG-- 127
            |.::|:. .||.  |||||..:.:.|:||.:.|   :...|..||.|::..|:.||||||.:|
  Rat   379 ESSDCTT-KINA--RIVGGTNSSLGEWPWQVSLQVKLVSQNHMCGGSIIGRQWILTAAHCFDGIP 440

  Fly   128 ------FYHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGID 186
                  .|..::.:..:.:....|.:|       .::||.||.......|||||:...|:.....
  Rat   441 YPDVWRIYGGILNLSEITNKTPFSSIK-------ELIIHQKYKMSEGSYDIALIKLQTPLNYTEF 498

  Fly   187 MHPVCMPTPSE-NYAGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNYGESKITDNMI 250
            ..|:|:|:.:: |.......|||||...|.|...:.||:..:|::..|||: ..|.:..||..||
  Rat   499 QKPICLPSKADTNTIYTNCWVTGWGYTKERGETQNILQKATIPLVPNEECQ-KKYRDYVITKQMI 562

  Fly   251 CAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENT 315
            |||| ::||.|:|:||||||:....|| .:||.||.|||||||:...|||||:|..:.|||.|..
  Rat   563 CAGY-KEGGIDACKGDSGGPLVCKHSG-RWQLVGITSWGEGCARKEQPGVYTKVAEYIDWILEKI 625

  Fly   316 RDA 318
            :.:
  Rat   626 QSS 628

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	90/240 (38%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	91/242 (38%)
Klkb1	NP_036857.2	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	201..284	CDD:128519
		APPLE	292..375	CDD:128519
		Tryp_SPc	390..621	CDD:214473	90/240 (38%)
		Tryp_SPc	391..621	CDD:238113	89/239 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45531
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810