DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and F9

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_113728.1	Gene:	F9 / 24946	RGDID:	2589	Length:	462	Species:	Rattus norvegicus

Alignment Length:	250	Identity:	86/250 - (34%)
Similarity:	136/250 - (54%)	Gaps:	21/250 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 INTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGFYHRLITVRLLEHN 141
            ||...|:|||:..:..:.||.::|......:||.:::|:::.:|||||:..  ...|.|...|||
  Rat   222 INDFTRVVGGENAKPGQIPWQVILNGEIEAFCGGAIINEKWIVTAAHCLKP--GDKIEVVAGEHN 284

  Fly   142 ---RQDSHVKIVDRRVSRVLIHPKYST--RNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENYAG 201
               ::|:..:   |.|.|.:.|.:|:.  ..:..||||:..::|:.|...:.|:|:  .::.|..
  Rat   285 IDEKEDTEQR---RNVIRTIPHHQYNATINKYSHDIALLELDKPLILNSYVTPICV--ANKEYTN 344

  Fly   202 -----QTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKD 261
                 .:..|:|||.:...|..:..||.:.||::.:..|..|.  :..|.:||.|||| .:||||
  Rat   345 IFLKFGSGYVSGWGKVFNKGRQASILQYLRVPLVDRATCLRST--KFSIYNNMFCAGY-REGGKD 406

  Fly   262 SCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENTR 316
            ||:|||||| ||........|.||:||||.||.....|:||:|..:.:||.|.|:
  Rat   407 SCEGDSGGP-HVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	80/238 (34%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	81/240 (34%)
F9	NP_113728.1	GLA	21..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	127..163	CDD:291342
		Tryp_SPc	227..455	CDD:214473	80/238 (34%)
		Tryp_SPc	228..458	CDD:238113	81/240 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm12321
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910