DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and CG30091

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster

Alignment Length:	293	Identity:	89/293 - (30%)
Similarity:	134/293 - (45%)	Gaps:	58/293 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 WSSPAKRECAEC---SCG-NINTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTA 121
            |...|.|..|..   .|| .:....:||||.:....:.|||.::.....|.||.|::.:::.|||
  Fly    11 WMLTAGRGSARLLDEDCGVPMQLIPKIVGGVDAGELKNPWMALIKTNDEFICGGSVITNKFVLTA 75

  Fly   122 AHCV----------------NGFYHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDS 170
            |||:                .|.||.|.|.   |||......     .|.||.||..::.:|:.:
  Fly    76 AHCMCTDEECIVKYTQLTVTLGVYHLLATG---EHNHPHEIY-----NVERVYIHDSFAIQNYRN 132

  Fly   171 DIALIRFNEPVRLGIDMHPVCMPTPSENYAGQTAVV-----TGWGALSEGGPISDTLQEVEVPIL 230
            ||||:|..:.:.....:.|:|: ..::....||.::     .||| ::..|.:|:.||.|::..:
  Fly   133 DIALLRLQKSIVYKPQIKPLCI-LLNDQLKPQTDLIQEFTAIGWG-VTGNGKMSNNLQMVKIYRI 195

  Fly   231 SQEECRNS-----NYGESKITDNMICAGYVEQGGKDSCQGDSGGPM--HVLGSG--DAYQLAGIV 286
            .::.|..:     :|       .|.|||...  |:|:|:.|||||:  |:|..|  .|.|| |||
  Fly   196 DRKMCEAAFWYTFDY-------PMFCAGTAV--GRDTCKRDSGGPLYIHMLFDGIKRATQL-GIV 250

  Fly   287 SWG-EGCAKPNAPGVYTRVGSFNDWIAENTRDA 318
            |.| |.|   ...|:||.|....|:|.....||
  Fly   251 STGTEDC---RGFGMYTDVMGHIDFIERIVLDA 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	80/259 (31%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	81/261 (31%)
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	80/259 (31%)
		Tryp_SPc	37..276	CDD:238113	81/261 (31%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910