DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and Mst1

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_038936729.1	Gene:	Mst1 / 24566	RGDID:	3114	Length:	747	Species:	Rattus norvegicus

Alignment Length:	292	Identity:	83/292 - (28%)
Similarity:	131/292 - (44%)	Gaps:	35/292 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 DPEKILNNLAQLRQSSFLDWIQSILGPEVPAEWSSPAKRECAECSCGNINTRHRIVGGQETEVHE 93
            |||.:.:..|..|...  |...|||.|.|..::....||.       :.:.|.|:|||..   ..
  Rat   475 DPETLFDYCALKRCDD--DQPPSILDPPVQVQFEKCGKRV-------DQSNRLRVVGGHP---GN 527

  Fly    94 YPWMIMLM-WFGNFYCGASLVNDQYALTAAHCVNGFYHRL----ITVRLLEHNRQDSHVKIVDRR 153
            .||.:.|. ..|..:||.|||.:|:.|||..|:...:..|    :.:..:..|.|.....:....
  Rat   528 SPWTVSLRNRQGQHFCGGSLVKEQWVLTARQCIWSCHDPLTGYEVWLGTINQNPQPGEANLQRVS 592

  Fly   154 VSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENYA---GQTAVVTGWGALSEG 215
            |::.:..|.      .|.:.|::...||.|...:..:|:  |.|.|.   |....:.|||. |:|
  Rat   593 VAKTVCGPA------GSQLVLLKLERPVILNHHVARICL--PPEQYVVPPGTNCEIAGWGE-SKG 648

  Fly   216 GPISDTLQEVEVPILSQEECRNSNYGESKITDNMICA-GYVEQGGKDSCQGDSGGPMHVLGSGDA 279
            ...|..|...::.::|.:|| |..| ..::.::.||. |.:...|  :|:||.|||: ...:.|.
  Rat   649 TSNSTVLHVAKMKVISSQEC-NVKY-RRRVQESEICTEGLLAPTG--ACEGDYGGPL-ACYTHDC 708

  Fly   280 YQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWI 311
            :.|.|::.....||:|..|.::|||..|.|||
  Rat   709 WVLQGLIIPNRVCARPRWPAIFTRVSVFVDWI 740

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	67/237 (28%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	68/238 (29%)
Mst1	XP_038936729.1	PAN_1	32..111	CDD:394981
		KR	116..196	CDD:214527
		KR	199..276	CDD:214527
		KR	321..403	CDD:214527
		KR	408..490	CDD:214527	5/14 (36%)
		Tryp_SPc	520..743	CDD:238113	68/238 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910