DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and Hp

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_036714.2	Gene:	Hp / 24464	RGDID:	2825	Length:	347	Species:	Rattus norvegicus

Alignment Length:	354	Identity:	85/354 - (24%)
Similarity:	139/354 - (39%)	Gaps:	87/354 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 ATALGDLACATP--------------------SLRSASDPEKILNNLAQLRQSSFLDWIQSILGP 55
            ||.:.|.:|..|                    .|::..|....||:..|        |:....|.
  Rat    25 ATDIEDDSCPKPPEIANGYVEHLVRYRCRQFYKLQTEGDGIYTLNSEKQ--------WVNPAAGD 81

  Fly    56 EVPAEWSSPAKRECAECSCGN----INTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQ 116
            ::|         :| |..||.    ::...||:||.......:||...::.......||:|::||
  Rat    82 KLP---------KC-EAVCGKPKHPVDQVQRIIGGSMDAKGSFPWQAKMISRHGLTTGATLISDQ 136

  Fly   117 YALTAAHCVNGFYHRLITVRLLEHNRQDSHVKIVDR-----------RVSRVLIHPKYSTRNFDS 170
            :.||.|.  |.|         |.|:...:...|...           .:.:|::||:.|.    .
  Rat   137 WLLTTAQ--NLF---------LNHSENATAKDIAPTLTLYVGKNQLVEIEKVVLHPERSV----V 186

  Fly   171 DIALIRFNEPVRLGIDMHPVCMPTPSENYAGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEEC 235
            ||.||:..:.|.:...:.|:|:|:......|:...|:|||. :.....::.|:.|.:|:..||:|
  Rat   187 DIGLIKLKQKVLVTEKVMPICLPSKDYVAPGRMGYVSGWGR-NVNFRFTERLKYVMLPVADQEKC 250

  Fly   236 ----RNSNYGESK-----------ITDNMICAGYVEQGGKDSCQGDSGGPMHVLGS-GDAYQLAG 284
                ..|...|.|           :..:..|||..:. .:|:|.||:|....|..: .|.:..||
  Rat   251 ELHYEKSTVPEKKGAVSPVGVQPILNKHTFCAGLTKY-EEDTCYGDAGSAFAVHDTEEDTWYAAG 314

  Fly   285 IVSWGEGCAKPNAPGVYTRVGSFNDWIAE 313
            |:|:.:.||.... |||.|.....||:.|
  Rat   315 ILSFDKSCAVAEY-GVYVRATDLKDWVQE 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	66/255 (26%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	67/258 (26%)
Hp	NP_036714.2	CCP	33..87	CDD:153056	11/71 (15%)
		Tryp_SPc	102..340	CDD:214473	66/255 (26%)
		Tryp_SPc	103..343	CDD:238113	67/258 (26%)
		Interaction with CD163. /evidence=ECO:0000250	259..264		1/4 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910