DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18735 and Hgf

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_058713.1	Gene:	Hgf / 24446	RGDID:	2794	Length:	728	Species:	Rattus norvegicus

Alignment Length:	282	Identity:	67/282 - (23%)
Similarity:	123/282 - (43%)	Gaps:	45/282 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 PEVPAEWSSPAKRECAECSCGNINTRH-----------RIVGGQETEVHEYPWMIMLMWFGNFYC 108
            |.||.:: .|..|...:.:...:|..|           |:|.|..|:. ...||:.|.:.....|
  Rat   458 PLVPWDY-CPISRCEGDTTPTIVNLDHPVISCAKTKQLRVVNGIPTQT-TVGWMVSLKYRNKHIC 520

  Fly   109 GASLVNDQYALTAAHCVNG------FYHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRN 167
            |.||:.:.:.|||..|...      .|...:.:..:....::...:|::  :|:::..|:
  Rat   521 GGSLIKESWVLTARQCFPARNKDLKDYEAWLGIHDVHERGEEKRKQILN--ISQLVYGPE----- 578

  Fly   168 FDSDIALIRFNEPVRLGIDMHPVCMPT-----PSENYAGQTAVVTGW---GALSEGGPISDTLQE 224
             .||:.|::...|..|...:..:.:|:     |.:.    |..:.||   |.::..|    .|:.
  Rat   579 -GSDLVLLKLARPAILDNFVSTIDLPSYGCTIPEKT----TCSIYGWGYTGLINADG----LLRV 634

  Fly   225 VEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWG 289
            ..:.|:..|:|...:.|:..:.::.:||| .|:.|...|:||.|||: :........:.|::..|
  Rat   635 AHLYIMGNEKCSQHHQGKVTLNESELCAG-AEKIGSGPCEGDYGGPL-ICEQHKMRMVLGVIVPG 697

  Fly   290 EGCAKPNAPGVYTRVGSFNDWI 311
            .|||.||.||::.||..:..||
  Rat   698 RGCAIPNRPGIFVRVAYYAKWI 719

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	58/242 (24%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	59/243 (24%)
Hgf	NP_058713.1	PAN_APPLE	41..123	CDD:238074
		KR	127..209	CDD:214527
		KR	211..289	CDD:214527
		KR	305..385	CDD:214527
		KR	389..471	CDD:238056	5/13 (38%)
		Tryp_SPc	495..719	CDD:214473	58/242 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910