DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18735 and Prss50

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_666339.2	Gene:	Prss50 / 235631	MGIID:	2447303	Length:	439	Species:	Mus musculus

Alignment Length:	291	Identity:	74/291 - (25%)
Similarity:	120/291 - (41%)	Gaps:	67/291 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 CGNINTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGFYHRLITVRLL 138
            ||:.:.....:...|.....:|||:.:...|:..|...|:..|:.||.|||::
Mouse   158 CGSSHEPDPTLRDPEAMTRRWPWMVSVQANGSHICAGILIASQWVLTVAHCLS------------ 210

  Fly   139 EHNRQDSHVKIV----------------DRRVSRVLIHPKYSTRNFDS------DIALIRFNEPV 181
                 .:||..:                |..|.||:|:..|..|.:.|      ||.|::....:
Mouse   211 -----QNHVNYIVRAGSPWINQTAGTSSDVPVHRVIINHGYQPRRYWSWVGRAHDIGLLKLKWGL 270

  Fly   182 RLGIDMHPVCMPTPSENYA---GQTAVVTGWGALSEGG--PISDTLQEVEVPILSQEECRNSNYG 241
            :....:.|:|:  |..:|.   .....|||||.....|  |...:|||.||.||:.::|.:..:.
Mouse   271 KYSKYVWPICL--PGLDYVVEDSSLCTVTGWGYPRANGIWPQFQSLQEKEVSILNSKKCDHFYHK 333

  Fly   242 ESKITD-------NMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPG 299
            .|:|:.       .||||.  :...::.|...:|.|: |..|...:.|.|::|||.||.|..||.
Mouse   334 FSRISSLVRIINPQMICAS--DNNREEFCYEITGEPL-VCSSDGTWYLVGMMSWGPGCKKSEAPP 395

  Fly   300 VYTRVGSFNDWIAENTRDACSCAQPEAAGEP 330
            ::.:|..:..||.:           ..:|||
Mouse   396 IFLQVSYYRPWIWD-----------RLSGEP 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	67/262 (26%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	69/264 (26%)
Prss50	NP_666339.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	48..130
		Tryp_SPc	177..407	CDD:214473	66/251 (26%)
		Tryp_SPc	177..407	CDD:238113	66/251 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910