Protein Alignment CG18735 and F11

DIOPT Version :10

• Sequence 1: NP_652645.1
• Gene: CG18735 / 59137
• FlyBaseID: FBgn0042098
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: XP_005262878.1
• Gene: F11 / 2160
• HGNCID: 3529
• Length: 626
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 105/306 - (34%)
• Similarity: 145/306 - (47%)
• Gaps: 45/306 - (14%)

  Fly    24 LRSASDPEKILNNLAQLRQSSFLDWIQSILGPEVPAEWSSPAKRECA---ECSCGNINTRHRIVG 85
            |.|...|.|||:....:                     |....|.|.   ||:   ...:.||||
Human   351 LSSNGSPTKILHGRGGI---------------------SGYTLRLCKMDNECT---TKIKPRIVG 391

  Fly    86 GQETEVHEYPWMIMLMWFG---NFYCGASLVNDQYALTAAHCVNGFYHRLITVRLLEHNRQDSHV 147
            |..:...|:||.:.|....   ...||.|::.:|:.||||||..|.....| :|:.......|.:
Human   392 GTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKI-LRVYSGILNQSEI 455

  Fly   148 KIVDRR---VSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSE-NYAGQTAVVTG 208
            | .|..   |..::||.:|.......||||::....|.......|:|:|:..: |.......|||
Human   456 K-EDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTG 519

  Fly   209 WGALSEGGPISDTLQEVEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDSCQGDSGGPM-- 271
            ||.......|.:|||:.::|:::.|||: ..|...|||..|||||| .:||||:|:||||||:
Human   520 WGYRKLRDKIQNTLQKAKIPLVTNEECQ-KRYRGHKITHKMICAGY-REGGKDACKGDSGGPLSC 582

  Fly   272 -HVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENTR 316
             |    .:.:.|.||.|||||||:...|||||.|..:.|||.|.|:
Human   583 KH----NEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQ 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	91/240 (38%)
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519	8/44 (18%)
		Tryp_SPc	389..619	CDD:238113	89/237 (38%)