Protein Alignment CG18735 and F9

DIOPT Version :10

• Sequence 1: NP_652645.1
• Gene: CG18735 / 59137
• FlyBaseID: FBgn0042098
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: NP_000124.1
• Gene: F9 / 2158
• HGNCID: 3551
• Length: 461
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 95/298 - (31%)
• Similarity: 150/298 - (50%)
• Gaps: 48/298 - (16%)

  Fly    26 SASDPEKILNNLAQLRQSSFLDWIQSILGPEVPAEWSSPAKRECAECSCGNINTRHRIVGGQETE 90
            ::::.|.||:|:.|..||                                 .|...|:|||::.:
Human   203 NSTEAETILDNITQSTQS---------------------------------FNDFTRVVGGEDAK 234

  Fly    91 VHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGFYHRLITVRLLEHNRQDSHVKIVDRRVS 155
            ..::||.::|....:.:||.|:||:::.:||||||.....  |||...|||.:::......|.|.
Human   235 PGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVK--ITVVAGEHNIEETEHTEQKRNVI 297

  Fly   156 RVLIHPKYST--RNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENYAG-----QTAVVTGWGALS 213
            |::.|..|:.  ..::.||||:..:||:.|...:.|:|:  ..:.|..     .:..|:|||.:.
Human   298 RIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICI--ADKEYTNIFLKFGSGYVSGWGRVF 360

  Fly   214 EGGPISDTLQEVEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGD 278
            ..|..:..||.:.||::.:..|..|.  :..|.:||.|||: .:||:|||||||||| ||.....
Human   361 HKGRSALVLQYLRVPLVDRATCLRST--KFTIYNNMFCAGF-HEGGRDSCQGDSGGP-HVTEVEG 421

  Fly   279 AYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENTR 316
            ...|.||:||||.||.....|:||:|..:.:||.|.|:
Human   422 TSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	84/237 (35%)
F9	NP_000124.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:464251
		Tryp_SPc	227..457	CDD:238113	84/237 (35%)