DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and Tmprss13

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_006510195.1	Gene:	Tmprss13 / 214531	MGIID:	2682935	Length:	561	Species:	Mus musculus

Alignment Length:	257	Identity:	93/257 - (36%)
Similarity:	144/257 - (56%)	Gaps:	16/257 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 PAKRECA-ECS-CGNINTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVN 126
            |::|..: :|| ||......|||||..|...::||.:.|.:.....||.:|::.|:.||||||
Mouse   299 PSRRYVSLQCSHCGLRAMTGRIVGGALTSESKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHC-- 361

  Fly   127 GFYHRLITVRLLE-----HNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGID 186
             |:  :...:|||     ....:.|.......:|:::|:..|:....|.||||||.::|:.|...
Mouse   362 -FF--VTREKLLEGWKVYAGTSNLHQLPEAASISQIIINGNYTDEQDDYDIALIRLSKPLTLSAH 423

  Fly   187 MHPVCMPTPSENYA-GQTAVVTGWGALSE-GGPISDTLQEVEVPILSQEECRNSNYGESKITDNM 249
            :||.|:|...:.:. .:|..:||:|...| ....|..|:||:|.::..::|.:....:|.:|..|
Mouse   424 IHPACLPMHGQTFGLNETCWITGFGKTKETDEKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRM 488

  Fly   250 ICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWI 311
            :|||.: :||:||||||||||: |....:.:.|||:.|||.||.:.|.|||||:|.....||
Mouse   489 MCAGDL-RGGRDSCQGDSGGPL-VCEQNNRWYLAGVTSWGTGCGQKNKPGVYTKVTEVLPWI 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	85/235 (36%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	86/236 (36%)
Tmprss13	XP_006510195.1	PHA03378	<6..>122	CDD:223065
		LDLa	<204..220	CDD:238060
		SRCR_2	225..314	CDD:373897	6/14 (43%)
		Tryp_SPc	319..548	CDD:214473	85/235 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910