DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18735 and Prss12

DIOPT Version :9

Sequence 1:NP_652645.1 Gene:CG18735 / 59137 FlyBaseID:FBgn0042098 Length:364 Species:Drosophila melanogaster
Sequence 2:NP_032965.1 Gene:Prss12 / 19142 MGIID:1100881 Length:761 Species:Mus musculus


Alignment Length:283 Identity:93/283 - (32%)
Similarity:129/283 - (45%) Gaps:45/283 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    62 SSPAKRECAECSCGNINTRH----RIVGGQETEVHEYPWMIMLM-----WFGNFYCGASLVNDQY 117
            ||...:|.....|| :...|    ||:||..:....:||...|.     ..|...|||:|::..:
Mouse   493 SSSGNKEMLSSGCG-LRLLHRRQKRIIGGNNSLRGAWPWQASLRLRSAHGDGRLLCGATLLSSCW 556

  Fly   118 ALTAAHCVN-------------GFYHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFD 169
            .||||||..             |.||.|:.    |...|:..|:       :::||..|.....|
Mouse   557 VLTAAHCFKRYGNNSRSYAVRVGDYHTLVP----EEFEQEIGVQ-------QIVIHRNYRPDRSD 610

  Fly   170 SDIALIRFNEP----VRLGIDMHPVCMPTPSE--NYAGQTAVVTGWGALSEGGPISDTLQEVEVP 228
            .||||:|...|    .||...:.|.|:|...|  ........:||||  ..|...|.|||:..||
Mouse   611 YDIALVRLQGPGEQCARLSTHVLPACLPLWRERPQKTASNCHITGWG--DTGRAYSRTLQQAAVP 673

  Fly   229 ILSQEECRNSNYGESKITDNMICAGYVEQGGK-DSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGC 292
            :|.:..|:....|  ..|..|:|||.:::..: ||||||||||:......:::.:.|:.|||.||
Mouse   674 LLPKRFCKERYKG--LFTGRMLCAGNLQEDNRVDSCQGDSGGPLMCEKPDESWVVYGVTSWGYGC 736

  Fly   293 AKPNAPGVYTRVGSFNDWIAENT 315
            ...:.|||||||.:|..||...|
Mouse   737 GVKDTPGVYTRVPAFVPWIKSVT 759

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18735NP_652645.1 Tryp_SPc 82..311 CDD:214473 84/253 (33%)
Tryp_SPc 83..314 CDD:238113 85/255 (33%)
Prss12NP_032965.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 25..87
KR 83..159 CDD:214527
SR 166..265 CDD:214555
SRCR 171..265 CDD:278931
SR 273..372 CDD:214555
SRCR 278..371 CDD:278931
SR 386..485 CDD:214555
SRCR 396..485 CDD:278931
Zymogen activation region 505..516 3/11 (27%)
Tryp_SPc 516..755 CDD:214473 84/253 (33%)
Tryp_SPc 517..758 CDD:238113 85/255 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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