DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and svh-1

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_501379.2	Gene:	svh-1 / 182375	WormBaseID:	WBGene00006620	Length:	951	Species:	Caenorhabditis elegans

Alignment Length:	266	Identity:	91/266 - (34%)
Similarity:	142/266 - (53%)	Gaps:	42/266 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 CG----NINTRH-------RIVGGQETEVHEYPWMIMLMWFGN-----FYCGASLVNDQYALTAA 122
            ||    .:|.|.       |:|||.||....:||...|.   |     .:||||:::..:.:|||
Worm   693 CGLRYVEVNARDAAKSRIARVVGGFETVPGAFPWTAALR---NKATKAHHCGASILDKTHLITAA 754

  Fly   123 HC------VNGFYHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPV 181
            ||      |:.:.   :.|...::|:.|.:.:|.  .:.|:..:|.|.. .|..|||::....|
Worm   755 HCFEEDERVSSYE---VVVGDWDNNQTDGNEQIF--YLQRIHFYPLYKD-IFSHDIAILEIPYP- 812

  Fly   182 RLGIDMH----PVCMPTPSENYA-GQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNYG 241
              ||:.:    |:|:|:....|. |:..||:|||::  |...::.||...:||:::.:|.||:..
Worm   813 --GIEFNEYAQPICLPSKDFVYTPGRQCVVSGWGSM--GLRYAERLQAALIPIINRFDCVNSSQI 873

  Fly   242 ESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGS 306
            .|.::.:..||||:| ||.||||||||||........|:.|||::|||:|||:...||:||.|..
Worm   874 YSSMSRSAFCAGYLE-GGIDSCQGDSGGPFACRREDGAFVLAGVISWGDGCAQKKQPGIYTMVAP 937

  Fly   307 FNDWIA 312
            :..||:
Worm   938 YLSWIS 943

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	85/244 (35%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	86/246 (35%)
svh-1	NP_501379.2	KR	227..306	CDD:214527
		LDLa	320..355	CDD:238060
		PAN_AP_HGF	373..434	CDD:238532
		LDLa	558..590	CDD:197566
		SRCR_2	599..681	CDD:382996
		Tryp_SPc	713..945	CDD:238113	86/246 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14756
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910