DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and Masp1

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_036015702.1	Gene:	Masp1 / 17174	MGIID:	88492	Length:	746	Species:	Mus musculus

Alignment Length:	323	Identity:	101/323 - (31%)
Similarity:	148/323 - (45%)	Gaps:	69/323 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 KILNNLAQLRQ-SSFLDWIQSILGPEVPAEWSSPAKRECAEC--SCG----NINTRHRIVGGQET 89
            |:|:|...:.. |:...|...:|            ||....|  .||    :.....||..|:..
Mouse   408 KMLHNTTGVYTCSAHGTWTNEVL------------KRSLPTCLPVCGVPKFSRKQISRIFNGRPA 460

  Fly    90 EVHEYPWMIMLMWF-GNFYCGASLVNDQYALTAAHCVN-------------------------GF 128
            :....||:.||... |..:||.||:...:.||||||::                         |.
Mouse   461 QKGTMPWIAMLSHLNGQPFCGGSLLGSNWVLTAAHCLHQSLDPEEPTLHSSYLLSPSDFKIIMGK 525

  Fly   129 YHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMP 193
            :.|    |..:.:.|..|||       |..:||.|:...|::|:.|:..:|..||...:.|||:|
Mouse   526 HWR----RRSDEDEQHLHVK-------RTTLHPLYNPSTFENDLGLVELSESPRLNDFVMPVCLP 579

  Fly   194 -TPSENYAGQTAVVTGWGA--LSEGGPISDTLQEVEVPILSQEECRNSNYG--ESKITDNMICAG 253
             .||..  |...:|:|||.  |..   ..:.|.|:|:||::.:.|:.: |.  :.|:|.:|||||
Mouse   580 EQPSTE--GTMVIVSGWGKQFLQR---FPENLMEIEIPIVNSDTCQEA-YTPLKKKVTKDMICAG 638

  Fly   254 YVEQGGKDSCQGDSGGPMHVL-GSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENT 315
             .::||||:|.|||||||... ...|.:.|.|:|||||.|.|.:..|||:.:....|||...|
Mouse   639 -EKEGGKDACAGDSGGPMVTKDAERDQWYLVGVVSWGEDCGKKDRYGVYSYIYPNKDWIQRIT 700

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	87/260 (33%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	88/262 (34%)
Masp1	XP_036015702.1	CUB	33..142	CDD:238001
		FXa_inhibition	158..186	CDD:405372
		CUB	190..299	CDD:395345
		PHA02639	<305..>438	CDD:165022	8/41 (20%)
		CCP	306..368	CDD:153056
		Tryp_SPc	454..699	CDD:238113	88/262 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910