DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and Hgf

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_001276387.1	Gene:	Hgf / 15234	MGIID:	96079	Length:	728	Species:	Mus musculus

Alignment Length:	244	Identity:	60/244 - (24%)
Similarity:	111/244 - (45%)	Gaps:	33/244 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 RIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNG------FYHRLITVRLLEH 140
            |:|.|..|:. ...||:.|.:.....||.||:.:.:.|||..|...      .|...:.:..:..
Mouse   495 RVVNGIPTQT-TVGWMVSLKYRNKHICGGSLIKESWVLTARQCFPARNKDLKDYEAWLGIHDVHE 558

  Fly   141 NRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPT-----PSENYA 200
            ..::...:|::  :|:::..|:      .||:.|::...|..|...:..:.:|:     |.:.
Mouse   559 RGEEKRKQILN--ISQLVYGPE------GSDLVLLKLARPAILDNFVSTIDLPSYGCTIPEKT-- 613

  Fly   201 GQTAVVTGW---GALSEGGPISDTLQEVEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDS 262
              |..:.||   |.::..|    .|:...:.|:..|:|...:.|:..:.::.:||| .|:.|...
Mouse   614 --TCSIYGWGYTGLINADG----LLRVAHLYIMGNEKCSQHHQGKVTLNESELCAG-AEKIGSGP 671

  Fly   263 CQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWI 311
            |:||.|||: :........:.|::..|.|||.||.||::.||..:..||
Mouse   672 CEGDYGGPL-ICEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWI 719

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	58/242 (24%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	59/243 (24%)
Hgf	NP_001276387.1	PAN_APPLE	41..123	CDD:238074
		KR	127..209	CDD:214527
		KR	211..289	CDD:214527
		KR	305..385	CDD:214527
		KR	389..471	CDD:238056
		Tryp_SPc	495..719	CDD:214473	58/242 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910