DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and Tmprss3

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_001157248.1	Gene:	Tmprss3 / 140765	MGIID:	2155445	Length:	475	Species:	Mus musculus

Alignment Length:	315	Identity:	115/315 - (36%)
Similarity:	170/315 - (53%)	Gaps:	27/315 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LACAT---PSLRSASDPEKILNNLAQLRQSSFLDWIQSILGPEVPAEWSSPAKRE-CA------- 70
            :|||.   ||..| ||..:: :.|.:..|..|:.....:...:|.|...|...|| |.
Mouse   162 IACAQLGFPSYVS-SDHLRV-DALEEQFQGDFVSINHLLSDDKVTALHHSVYMREGCTSGHVVTL 224

  Fly    71 ECS-CGNINTR----HRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGFYH 130
            :|| ||   ||    .|||||..:.:.::||.:.|.:.|...||.|::...:.:||||||...||
Mouse   225 KCSACG---TRTGYSPRIVGGNMSSLTQWPWQVSLQFQGYHLCGGSIITPLWIVTAAHCVYDLYH 286

  Fly   131 -RLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPT 194
             :..||::...:..||.|.  ...|.:::.|.||..:...:||||::.:||:.....:.|:|:|.
Mouse   287 PKSWTVQVGLVSLMDSPVP--SHLVEKIIYHSKYKPKRLGNDIALMKLSEPLTFDETIQPICLPN 349

  Fly   195 PSENYA-GQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNYGESKITDNMICAGYVEQG 258
            ..||:. |:....:||||..:||..|..|....||::|.:.|.:.:.....|:.:|:||||: :|
Mouse   350 SEENFPDGKLCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYL-KG 413

  Fly   259 GKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAE 313
            |.||||||||||: |......::|.|..|:|.|||:.|.||||||:.||.|||.|
Mouse   414 GVDSCQGDSGGPL-VCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHE 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	89/230 (39%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	91/233 (39%)
Tmprss3	NP_001157248.1	LDLa	96..129	CDD:238060
		SRCR_2	134..233	CDD:292133	22/75 (29%)
		Tryp_SPc	238..465	CDD:214473	89/230 (39%)
		Tryp_SPc	239..468	CDD:238113	91/233 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm11120
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810