Protein Alignment CG18735 and TMPRSS11B

DIOPT Version :9

• Sequence 1: NP_652645.1
• Gene: CG18735 / 59137
• FlyBaseID: FBgn0042098
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: NP_872308.2
• Gene: TMPRSS11B / 132724
• HGNCID: 25398
• Length: 416
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 108/317 - (34%)
• Similarity: 153/317 - (48%)
• Gaps: 45/317 - (14%)

  Fly    22 PSLRSASDPEKILNNLAQLRQSSFLDWIQSILGPEVPA-----EWSSPAKRECAECSCG-----N 76
            |.....|...||...|.|:.:::...|      ..|||     |.|..|........||     :
Human   120 PPAEGVSMRTKIKAKLHQMLKNNMASW------NAVPASIKLMEISKAASEMLTNNCCGRQVANS 178

  Fly    77 INTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGFYHRLITVRLLEHN 141
            |.|.::||.|:.:....:||...:.|.|..||||||::.::.|:||||.           ..::|
Human   179 IITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCF-----------AKKNN 232

  Fly   142 RQDSHVKI--------VDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPTP--- 195
            .:|..|..        :.|:|..::.|..||:.....||||::..|.|.....:..:|:|..
Human   233 SKDWTVNFGIVVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMK 297

  Fly   196 -SENYAGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNYGESK-ITDNMICAGYVEQG 258
             |||   ...||||||.|...|.....|||..:.|:..:.| |::|..|. :||.|:|||:: .|
Human   298 LSEN---DNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKIC-NASYAYSGFVTDTMLCAGFM-SG 357

  Fly   259 GKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENT 315
            ..|:||.|||||:....|.:.:.|.||||||:||.|.|.|||||||.|:.:||...|
Human   358 EADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWITSKT 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	88/241 (37%)
		Tryp_SPc	83..314	CDD:238113	90/243 (37%)
TMPRSS11B	NP_872308.2	SEA	45..143	CDD:279699	6/22 (27%)
		Tryp_SPc	184..410	CDD:214473	88/241 (37%)
		Tryp_SPc	185..413	CDD:238113	90/243 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380103at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41415
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920