DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and AgaP_AGAP001365

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_321778.5	Gene:	AgaP_AGAP001365 / 1281817	VectorBaseID:	AGAP001365	Length:	608	Species:	Anopheles gambiae

Alignment Length:	253	Identity:	76/253 - (30%)
Similarity:	116/253 - (45%)	Gaps:	27/253 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 RHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGFYHRLITVRLLEHNRQD 144
            |.||:||..:...|:||.:.:.....:.||.|::..::.||||||:.    |..|...|:.:...
Mosquito   361 RSRIIGGVTSNQGEHPWHVAIYLDEEYQCGGSIIGRRWILTAAHCLT----RQNTNETLDVDLFR 421

  Fly   145 SHVKIVD---------RRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCM---PTPSE 197
            .:..|:|         |....|::|..|:...:.:||.|:|....:.....:.|||:   .....
Mosquito   422 VYTGIIDISTIDDHFYRTADEVIVHRDYNPVMYTTDIGLLRLKRNITYNSFIKPVCLYNRTVDIS 486

  Fly   198 NYAGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEEC--RNSNYGESKITDNMICAGYVEQGGK 260
            .:.|:...||||| .:..|.||:.|..:|||::||:.|  ||..:..........|||:.:  |.
Mosquito   487 TFYGREGKVTGWG-FNRDGVISNVLNYLEVPVVSQKMCSQRNVQFNGVLAVGESFCAGHAD--GN 548

  Fly   261 DSCQGDSGGPMHVLGSGDAYQLAGIVSWGEG-----CAKPNAPGVYTRVGSFNDWIAE 313
            ..|.|||||.: |...|..|.:.||||....     ...||...|:|.|..|.:||.:
Mosquito   549 SVCNGDSGGGL-VFAEGPRYYVRGIVSISAQRRNLLLCDPNQYSVFTDVSKFLNWIRQ 605

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	73/247 (30%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	74/250 (30%)
AgaP_AGAP001365	XP_321778.5	GD_N	42..144	CDD:292649
		GD_N	190..297	CDD:292649
		Tryp_SPc	363..603	CDD:214473	73/247 (30%)
		Tryp_SPc	364..606	CDD:238113	74/250 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910