DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and AgaP_AGAP011719

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_320793.4	Gene:	AgaP_AGAP011719 / 1280920	VectorBaseID:	AGAP011719	Length:	762	Species:	Anopheles gambiae

Alignment Length:	255	Identity:	67/255 - (26%)
Similarity:	113/255 - (44%)	Gaps:	53/255 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 CGASLVNDQYALTAAHC-------VNGFYHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYST 165
            ||.||:.:.|.||||||       ::....|:..:.|.:   .|....:.:|::.:::.||.::.
Mosquito    49 CGGSLIWENYILTAAHCYADPDTILSPDVIRIGDLNLFD---ADDDEFVQERKIVQIIRHPLHNA 110

  Fly   166 RNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENYAGQTAVVTGWGALSEGGPISDTLQEVEVPIL 230
            .....|:||::.::.|.....:.|.|: ...::....|..|.|||....|...|:.|.:.|:.::
Mosquito   111 STVYYDLALLKLDKKVIQSEGVIPTCL-WLDDSIPFSTLEVAGWGQTGFGKEKSNMLLKAELKLM 174

  Fly   231 SQEECRNSNYGESK------ITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQ-------L 282
            :..||...|...::      :.|:.:||.   ....|:|.||||||:|.    :.|.       |
Mosquito   175 TNTECAKYNNKRTQRRLGNDLADHQLCAW---DEVMDTCPGDSGGPLHY----NLYYKHTKIPFL 232

  Fly   283 AGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENTRDACSCAQPEAAGEPASPMETTEQGDQ 342
            .|:.|:|:.|| .:.||||.:|..|..||.|..:                     |||:|
Mosquito   233 VGVTSFGKACA-VSQPGVYVKVAKFKQWIIETLQ---------------------EQGEQ 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	60/222 (27%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	62/225 (28%)
AgaP_AGAP011719	XP_320793.4	Tryp_SPc	19..263	CDD:238113	62/225 (28%)
		Tryp_SPc	19..260	CDD:214473	60/222 (27%)
		Tryp_SPc	318..537	CDD:304450
		Tryp_SPc	653..>762	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910