DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and AgaP_AGAP011908

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_320621.4	Gene:	AgaP_AGAP011908 / 1280755	VectorBaseID:	AGAP011908	Length:	391	Species:	Anopheles gambiae

Alignment Length:	266	Identity:	85/266 - (31%)
Similarity:	139/266 - (52%)	Gaps:	30/266 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 ECSCGNINTRHRIVGGQETEVHEYPWMIMLM--WFGNFYCGASLVNDQYALTAAHCVNGFYHRLI 133
            ||.||...|. :||||....|:||..|:.|:  ...|.:|..::::.:|.||||||.     |.|
Mosquito   143 ECDCGWSRTA-KIVGGSVAGVNEYTAMVGLLDPLTVNVFCSGAIISSRYVLTAAHCA-----RTI 201

  Fly   134 ----TVRLL--EHNRQ---DSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHP 189
                .|:.|  :|:.:   |:....: ..:.:::.|..|:.:..::||||::.:..:.....:.|
Mosquito   202 PSVSRVQALVGDHDYRSGLDTPYSAI-YNIEQIISHEYYNEQTRNNDIALLKTSTEMDFNRGVGP 265

  Fly   190 VCMPTPSENYA--GQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNYGESKITDNMICA 252
            :|:|.....|:  |.:..:.|||..|.|||:|..|::..:.:|     :|:|.....:.|..||.
Mosquito   266 ICLPFTYSTYSFGGLSVDIAGWGTTSFGGPMSTILRKTTLNVL-----QNANCTAPYVNDQKICT 325

  Fly   253 GYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENTRD 317
            ..|   |:||||.||||.:.:.||...|.: ||:|:|..|| .:.|.|.|||.::..||.:||.:
Mosquito   326 FAV---GRDSCQYDSGGALFLRGSQRMYSI-GIISYGSACA-ASTPSVATRVTAYLSWIRQNTPE 385

  Fly   318 ACSCAQ 323
            ...||:
Mosquito   386 VSYCAK 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	74/241 (31%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	76/243 (31%)
AgaP_AGAP011908	XP_320621.4	CUB	26..>106	CDD:294042
		Tryp_SPc	153..379	CDD:214473	74/241 (31%)
		Tryp_SPc	154..382	CDD:238113	76/243 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910