DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and AgaP_AGAP012277

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_320261.4	Gene:	AgaP_AGAP012277 / 1280412	VectorBaseID:	AGAP012277	Length:	651	Species:	Anopheles gambiae

Alignment Length:	264	Identity:	66/264 - (25%)
Similarity:	128/264 - (48%)	Gaps:	30/264 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 SCG--NINTRHRIVGGQETEVHEYPWMIMLMW----FGNFYCGASLVNDQYALTAAHCV---NGF 128
            :||  .:.:.:.|..|.:.:...:||...:..    ...:.||.:::::...||||||:   .|.
Mosquito    29 TCGRRKVKSVYLIHNGIDAKAGHWPWHAAIFHRKGEQNEYACGGAVIDENTVLTAAHCIYTTRGI 93

  Fly   129 YHR-LITVRL--LEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPV 190
            ..: |:||.|  |:...:|.:.:  ...:..:::||||::.:..:||||::.:..:.:...:.||
Mosquito    94 IPKTLVTVHLGQLDLKEKDEYTQ--THSLQEIILHPKYNSSSIINDIALLKLSSHITMTKYVQPV 156

  Fly   191 C---MPTPSENYAGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSN---YGESKITDNM 249
            |   |.:..:...|:...:.|:| |:|...:|:.|::..:.::....|..|:   :| :.:|.:|
Mosquito   157 CLWTMDSKLDTIVGRNGTIVGFG-LNEQDVVSEQLKQALIGVVDPLTCIASDRSVFG-THLTSDM 219

  Fly   250 ICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSW-----GEGCAKPNAPGVYTRVGSFND 309
            .|.  ..|.|..:|.|||||.| ....|..:.:.|:||:     ..|...|.....||.|..:.:
Mosquito   220 FCG--KGQTGVSACNGDSGGGM-FFEVGGKWFVRGLVSFTPLRGNTGLCDPLKHTAYTDVAKYLE 281

  Fly   310 WIAE 313
            ||::
Mosquito   282 WISQ 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	62/249 (25%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	64/252 (25%)
AgaP_AGAP012277	XP_320261.4	Tryp_SPc	41..285	CDD:238113	64/250 (26%)
		Tryp_SPc	43..283	CDD:214473	61/246 (25%)
		Tryp_SPc	401..637	CDD:214473
		Tryp_SPc	401..637	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910