DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and AgaP_AGAP008403

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_317049.4	Gene:	AgaP_AGAP008403 / 1277577	VectorBaseID:	AGAP008403	Length:	873	Species:	Anopheles gambiae

Alignment Length:	253	Identity:	71/253 - (28%)
Similarity:	114/253 - (45%)	Gaps:	45/253 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 GQETEVHEYPWMIMLMWFG-----NFYCGASLVNDQYALTAAHCVNGFYHRL-ITVRLLEHNRQD 144
            |:...:.|:..|..:.|.|     ::.||.||:.:.|.||||||.....:.. ..|||.:.|..|
Mosquito    20 GRPAYLREFAHMAAVGWTGENGKIDWNCGGSLIWENYVLTAAHCTADDNNAAPDVVRLGDINLDD 84

  Fly   145 -------SHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCM------PTPS 196
                   ..:|||:     ::.||::...:...|:||:|....|.|...:.|.|:      |.||
Mosquito    85 DSDDKYAQQLKIVE-----IIRHPEHRFSSRYHDLALLRLERNVTLHDTVAPGCLWNDEEIPFPS 144

  Fly   197 ENYAGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEEC----RNSNYG-ESKITDNMICAGYVE 256
            ..       .||||  |.|...:..|.:|.:.::.:..|    |..:.| ...:.|..:|||.::
Mosquito   145 ME-------ATGWG--STGFAKTPILLKVSLSLVPKSTCDQQYRKGDRGLRQGLQDYQLCAGDIK 200

  Fly   257 QGGKDSCQGDSGGPMHVLGSGDAYQ---LAGIVSWGEGCAKPNAPGVYTRVGSFNDWI 311
            .   |:|.||||||:.:....:|..   :..:.|:|..|.: :.||||.:|..:..||
Mosquito   201 M---DTCPGDSGGPLQMKLLANAKMTPFIIAVTSFGSVCGQ-STPGVYMKVSPYIPWI 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	69/251 (27%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	71/253 (28%)
AgaP_AGAP008403	XP_317049.4	Tryp_SPc	20..256	CDD:238113	71/253 (28%)
		Tryp_SPc	20..254	CDD:214473	69/251 (27%)
		Tryp_SPc	324..552	CDD:304450
		CLIP	577..617	CDD:295450
		Tryp_SPc	656..872	CDD:304450
		Tryp_SPc	656..869	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910