DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and AgaP_AGAP004858

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_314333.4	Gene:	AgaP_AGAP004858 / 1275108	VectorBaseID:	AGAP004858	Length:	435	Species:	Anopheles gambiae

Alignment Length:	239	Identity:	67/239 - (28%)
Similarity:	111/239 - (46%)	Gaps:	31/239 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 NFYCGASLVNDQYALTAAHCV---NGFYHRLITVRLLE-----HNRQDSHVKIVDRRVSRVLIHP 161
            :|.||.||:..::.||||||.   :|...:::.:.:::     ::.|:...:  :..:|....||
Mosquito    14 SFDCGGSLITPRHVLTAAHCALNDDGVAPQVVRLGVIDITAGLYDPQNQFAQ--EYGISSFRRHP 76

  Fly   162 KYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENYAGQTAVVTGWGALSEGGPISDTLQEVE 226
            ::..|....||.|:..:.||.|...:.|.|:.|.::....:...| |:|..|.||..:..|.:|:
Mosquito    77 EHEFRAEYHDIGLVTLDRPVTLTDAVVPACLWTGAQVPLRRLEAV-GFGQTSFGGERTPILLKVQ 140

  Fly   227 VPILSQEEC-------RNSNYGESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQL-- 282
            :..:....|       |....|   :.|..:||   .....|:|.||||||:.:....:...:
Mosquito   141 LSPVDNSACGRFYPPSRRRRQG---LIDQQMCA---SDERMDTCHGDSGGPLQLKLMANNRLIPF 199

  Fly   283 -AGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENTR---DACSCA 322
             .||.|:|..|... .|.|||||.|:.||:...|.   ||.:||
Mosquito   200 VVGITSFGRFCGTA-TPAVYTRVSSYVDWLQTETGVSFDAKACA 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	61/223 (27%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	62/226 (27%)
AgaP_AGAP004858	XP_314333.4	Tryp_SPc	1..229	CDD:238113	62/224 (28%)
		Tryp_SPc	1..227	CDD:214473	60/222 (27%)
		Tryp_SPc	295..>384	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910