DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and AgaP_AGAP004568

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_313873.5	Gene:	AgaP_AGAP004568 / 1274710	VectorBaseID:	AGAP004568	Length:	283	Species:	Anopheles gambiae

Alignment Length:	257	Identity:	122/257 - (47%)
Similarity:	163/257 - (63%)	Gaps:	9/257 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 EC--SCGNINTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGFYHRLI 133
            :|  :||......:||||.|.|:..||||:.|.:...|.||.||:||:|.|||||||.|......
Mosquito    29 QCFAACGTNANNSKIVGGHEAEIGRYPWMVALYYNNRFICGGSLINDRYVLTAAHCVFGSDRSRF 93

  Fly   134 TVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNF-DSDIALIRFNEPVRLGIDMHPVCMPTPSE 197
            :|:.|.|:|........:|:||.::.:...:...| .:|:||::.:|||.||..:.|||:|....
Mosquito    94 SVKFLMHDRTVPKEDSFERKVSYIMTNWFLNVLVFITNDVALLKLSEPVPLGETIIPVCLPPEGN 158

  Fly   198 NYAGQTAVVTGWGALSEGG-PISDTLQEVEVPILSQEECRN-SNYGESKITDNMICAGYVEQGGK 260
            .||||..:|||||.|.:|. |:.  ||||.|||||.|:|.| :.|...:|.|.|:||| :.:|||
Mosquito   159 TYAGQEGIVTGWGKLGDGTFPMK--LQEVHVPILSNEQCHNQTQYFRFQINDRMMCAG-IPEGGK 220

  Fly   261 DSCQGDSGGPMHVLGS-GDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENTRDACSC 321
            |||||||||||||..: .:.:.:||:||||.|||:|..||:|.||..|..||..||||||:|
Mosquito   221 DSCQGDSGGPMHVFDTEANRFVIAGVVSWGFGCAQPRFPGIYARVNRFISWINFNTRDACTC 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	110/232 (47%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	112/234 (48%)
AgaP_AGAP004568	XP_313873.5	Tryp_SPc	42..272	CDD:214473	110/232 (47%)
AgaP_AGAP004568	XP_313873.5	Tryp_SPc	43..275	CDD:238113	112/234 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BJ04
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D19085at50557
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24256
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	5	4.920