DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and AgaP_AGAP003702

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_313494.5	Gene:	AgaP_AGAP003702 / 1274378	VectorBaseID:	AGAP003702	Length:	1532	Species:	Anopheles gambiae

Alignment Length:	304	Identity:	59/304 - (19%)
Similarity:	93/304 - (30%)	Gaps:	139/304 - (45%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 KRECAE------CSCGNINTRHRIVGGQETE----VHE----------------YPWMIMLMWFG 104
            ::||..      |||.|..|.|.  .|.:.:    .||                ||.....:|
Mosquito  1195 QQECKNTVGSYVCSCRNGYTLHD--NGHDCKESGCKHEIFTPHGQILSPNYPDYYPPKKDCIW-- 1255

  Fly   105 NFYCGASLVNDQYALTAAHCV----NGF---------YHRLITVRLLEHNRQDSHVKIVDRRVSR 156
                       .:..|..|.:    |.|         |..::   :.:.|..|||.  :.|....
Mosquito  1256 -----------HFTTTPGHRIRLVFNVFDIEPHQECAYDHIV---IYDGNSPDSHT--LGRFCGA 1304

  Fly   157 VLIHPKYSTRN-----FDSDIALIR-----------------------FNEPVRLGIDMHPVCMP 193
            .:.||..|:.|     |::|.::.|                       |...::.|..|:
Mosquito  1305 KIPHPISSSSNQMYMVFNTDTSVQRKGFFASHSTACGGRLKATEVKNHFYSHIKFGSGMY----- 1364

  Fly   194 TPSENYAGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNYGESKITDNMICA-GYVE- 256
               :|           ||..|...::|:.|.|::..||.|           :.:..:|: .|||
Mosquito  1365 ---DN-----------GADCEWTIVADSGQNVQLKFLSFE-----------LEEEKMCSYDYVEV 1404

  Fly   257 QGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGV 300
            .||.|    |..||:|                |:.|...|.|.:
Mosquito  1405 YGGLD----DESGPLH----------------GKYCGNANPPEI 1428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	51/282 (18%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	51/281 (18%)
AgaP_AGAP003702	XP_313494.5	PHA03420	<488..>565	CDD:177648
		ZnMc_BMP1_TLD	589..790	CDD:239808
		Astacin	596..789	CDD:279708
		CUB	792..905	CDD:278839
		CUB	909..1019	CDD:278839
		FXa_inhibition	1026..1061	CDD:291342
		CUB	1065..1180	CDD:278839
		FXa_inhibition	1187..1222	CDD:291342	9/28 (32%)
		CUB	1227..1336	CDD:278839	22/126 (17%)
		CUB	1340..1456	CDD:238001	28/139 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910