DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and CLIPB2

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_312956.3	Gene:	CLIPB2 / 1273920	VectorBaseID:	AGAP003246	Length:	355	Species:	Anopheles gambiae

Alignment Length:	301	Identity:	96/301 - (31%)
Similarity:	138/301 - (45%)	Gaps:	51/301 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 QLRQSSFLDWIQSILGPEVPAEWSSPAKRECAECSCGNINTRHRIVGGQETEVHEYPWMIMLMWF 103
            |.|.|||                  |...||      .|....||:|||.||:.|:||..::.:.
Mosquito    83 QTRTSSF------------------PTSPEC------GIQVTDRIIGGQTTELEEFPWTALIEYR 123

  Fly   104 --GN---FYCGASLVNDQYALTAAHCVNGFYH--RLITVRLLEHNRQDSH--------VKIVDRR 153
              ||   |:||.:|:|.:|.|||||||.....  :|..|||.|.:...::        ...:|..
Mosquito   124 KPGNQYDFHCGGALINARYILTAAHCVQSLPRGWQLNGVRLGEWDLSTANDCSDGICSAGPIDLE 188

  Fly   154 VSRVLIHPKYSTRN--FDSDIALIRFNEPVRLGIDMHPVCMPTP----SENYAGQTAVVTGWGAL 212
            :...:.|..|...:  ..:||||||..:.|.....:.|:|:|..    |.|..|..:...|||.
Mosquito   189 IESFVAHAGYDAADTAHTNDIALIRLRQDVASSEMIRPICLPLTEPQRSRNRVGTVSFAAGWGK- 252

  Fly   213 SEGGPISDTLQEVEVPILSQEECRNSNYG-ESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGS 276
            :|....|:...:||:.:.....||....| ...:..:.:|||.::  |||:|.||||||:....:
Mosquito   253 TESASASERKLKVELTVQDPSRCRQIYRGINIALKASQMCAGGLQ--GKDTCTGDSGGPLMAKSA 315

  Fly   277 GDAYQLAGIVSWG-EGCAKPNAPGVYTRVGSFNDWIAENTR 316
            | |:.|.|:||:| ..|.....|||||.|..:.|||..|.:
Mosquito   316 G-AWYLIGVVSFGLSKCGTAGYPGVYTNVVEYLDWIESNVQ 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	84/251 (33%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	85/253 (34%)
CLIPB2	XP_312956.3	CLIP	26..78	CDD:288855
		Tryp_SPc	102..350	CDD:214473	84/251 (33%)
		Tryp_SPc	103..353	CDD:238113	85/253 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25778
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	3	2.920