DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and AgaP_AGAP011325

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_309327.4	Gene:	AgaP_AGAP011325 / 1270612	VectorBaseID:	AGAP011325	Length:	631	Species:	Anopheles gambiae

Alignment Length:	319	Identity:	96/319 - (30%)
Similarity:	144/319 - (45%)	Gaps:	60/319 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 QSILGPEVPAEWSSP----------AKRECAEC---------------------SCGNINTRHRI 83
            |.|:.|:..:.|:.|          .:..||.|                     .||.. ...:|
Mosquito   322 QFIVYPDGVSRWTIPWLGFVRVGIEDEPRCAVCCQQEADSNNHRKRNLTLLDLEKCGPY-IEEKI 385

  Fly    84 VGGQETEVHEYPWMIMLMWFG-NFYCGASLVNDQYALTAAHCVNGFYHRL--ITVRLLEHNRQDS 145
            ..|.:..:.:||||.:|.... .|.||.:|:|.:|.||||||   |..:|  |:|||.|.:.: |
Mosquito   386 ANGIDAILFQYPWMALLQDTELAFVCGGTLINKRYVLTAAHC---FREKLSKISVRLGEFDLK-S 446

  Fly   146 HVKIVDRR------------VSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMP-TPSE 197
            .:. .|:|            |.|.:.|..||.|:..:||||||.........::.|:|:| :|..
Mosquito   447 DID-CDKRGERCALPPQDIAVERTIKHKDYSARHKVNDIALIRLASEASYNENVMPICLPVSPEM 510

  Fly   198 NYAGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNYGESK---ITDNMICAGYVEQGG 259
            ....:...|:||| |:|....||.||...:..|..:.|:.....:.|   :..:.:||  :....
Mosquito   511 RTVKEIYYVSGWG-LTENDTSSDVLQVGLLRQLPNDVCQQLLQRKDKYVTVNSDQMCA--IGANR 572

  Fly   260 KDSCQGDSGGPMHVLGSGDAYQLAGIVSWG-EGCAKPNAPGVYTRVGSFNDWIAENTRD 317
            .|:|.||||||:..:.....:...|:||:| ..|.|..||||||||.::.|||.:|..:
Mosquito   573 TDNCSGDSGGPLKTVAVNARFVQYGVVSYGLRTCGKETAPGVYTRVENYIDWILDNLEE 631

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	83/248 (33%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	85/250 (34%)
AgaP_AGAP011325	XP_309327.4	Tryp_SPc	44..287	CDD:238113
		Tryp_SPc	46..286	CDD:214473
		Tryp_SPc	384..625	CDD:214473	83/248 (33%)
		Tryp_SPc	385..625	CDD:238113	83/247 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	2	1.910