DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and AgaP_AGAP007043

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_001237132.2	Gene:	AgaP_AGAP007043 / 1270058	VectorBaseID:	AGAP007043	Length:	575	Species:	Anopheles gambiae

Alignment Length:	307	Identity:	72/307 - (23%)
Similarity:	131/307 - (42%)	Gaps:	61/307 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 LGPEVPAEWSSPAKR--------------ECAECSCG--NINTRHRIVGGQETEVHEYPWMIMLM 101
            :|..:...|..|.:.              |.|..:||  .::....:..|...|..::||.:.|
Mosquito     1 MGKVISECWGIPTQAVMALLVLLLIQQPFEVAASTCGVRRLSPMGLVTKGIIAEPGDWPWHVAL- 64

  Fly   102 WFGN-------FYCGASLVNDQYALTAAHCV---NGFYHRLITVRLLEHNRQDSHVKIVDRRVSR 156
             |.:       :.||.|:::..:.|:||||:   |..::.|...  :.|...|:...:|...:..
Mosquito    65 -FAHMKSEKPAYKCGGSIISQHFVLSAAHCIKEPNPDHYFLKAG--IHHLNNDNDTSVVVYNLFE 126

  Fly   157 VLIHPKYSTRNFDSDIALIRFNEPVRL-GIDMHPVCM-PTPSE---NYAGQTAVVTGWGALSEGG 216
            :::||||....|.:||||:|.:..:.. ...:.|:|: ||.:.   :...::.:..|:| ..|..
Mosquito   127 IILHPKYDRHTFYNDIALMRPDRAISFASFSIFPICLWPTHNATLIDVLSRSGIAVGFG-FDETH 190

  Fly   217 PISDTLQEVEVPILSQEECRNSNYGESKITDNM---------ICAGYVEQGGKDSCQGDSGGPMH 272
            .||:|||:..:.::.:::|      ..::.:::         :||...|.|. :.|.|||||.::
Mosquito   191 RISETLQQASMKVIEKQQC------IEQLPEHVRFLPQDAGKMCAIGTESGA-NVCSGDSGGGLY 248

  Fly   273 VLGSGDAYQLAGIVS--------WGEGCAKPNAPGVYTRVGSFNDWI 311
             ......:.|.||||        .||.......|..||.|..:..||
Mosquito   249 -FAKDQVWYLRGIVSAAARRDLDTGEATCNAALPATYTDVAQYTTWI 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	63/260 (24%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	65/261 (25%)
AgaP_AGAP007043	XP_001237132.2	Tryp_SPc	50..297	CDD:238113	65/258 (25%)
		Tryp_SPc	50..294	CDD:214473	63/256 (25%)
		Tryp_SPc	330..573	CDD:304450
		Tryp_SPc	330..570	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910