DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and AgaP_AGAP010635

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_307830.4	Gene:	AgaP_AGAP010635 / 1269219	VectorBaseID:	AGAP010635	Length:	569	Species:	Anopheles gambiae

Alignment Length:	321	Identity:	89/321 - (27%)
Similarity:	132/321 - (41%)	Gaps:	43/321 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 ECSCGNINTRHRIVGGQETEVHEYPWMIMLMWFG------NFYCGASLVNDQYALTAAHCVNGFY 129
            ||....:..:..:.||..|...::||...|...|      .:.||:::|:....:||||||....
Mosquito    36 ECGERLVKRQELVKGGYSTHPGDWPWHAALYHRGFNSRDFEYACGSTIVHRYLVITAAHCVTFAT 100

  Fly   130 HRL------ITVRLLEHNRQDSHVKIVDR-RVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDM 187
            .|.      :.:||...|..::..:..:. .|...::|..|.....::|||::|...|:.....:
Mosquito   101 SRRKIPSDNMQLRLGRFNLMNNEEEYAEEFSVIDTIVHEGYRPTTLENDIAILRVEIPIIFNDYI 165

  Fly   188 HPVCMPTPSE-----NYAGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSN---YGESK 244
            .|||:....:     |...|...|.||| |||...|..||.|.::|:::...|..|:   :|..
Mosquito   166 QPVCLWKRDDGFDLPNVYNQPGTVVGWG-LSENNRIGTTLNEAQMPVVNSWTCLASDRAFFGRF- 228

  Fly   245 ITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGE------GCAKPNAPGVYTR 303
            :.....||||  :.|...|.|||||.|........| |.||||:..      .|......| :|.
Mosquito   229 LQSKAFCAGY--KNGTGVCNGDSGGGMFFQFQNRWY-LKGIVSFSSVNDYSGWCNLRQYIG-FTD 289

  Fly   304 VGSFNDWIAENTRDACSCAQPEAAGEPASPMETTEQGDQENTTANGAAEADPEVEEANKLI 364
            ...:.||:.|||  ..|.......|.|  .|....||:      .|..|..||::|..|.|
Mosquito   290 ASQYIDWVYENT--PTSGNDDPILGHP--NMRLINQGN------CGRNEHMPEMDEDRKPI 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	70/255 (27%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	71/257 (28%)
AgaP_AGAP010635	XP_307830.4	Tryp_SPc	50..300	CDD:238113	71/255 (28%)
		Tryp_SPc	50..297	CDD:214473	70/252 (28%)
		Tryp_SPc	342..563	CDD:214473
		Tryp_SPc	342..563	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910