Protein Alignment CG18735 and CSMD2

DIOPT Version :9

• Sequence 1: NP_652645.1
• Gene: CG18735 / 59137
• FlyBaseID: FBgn0042098
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: NP_001268885.1
• Gene: CSMD2 / 114784
• HGNCID: 19290
• Length: 3631
• Species: Homo sapiens
• Alignment Length: 401
• Identity: 80/401 - (19%)
• Similarity: 121/401 - (30%)
• Gaps: 147/401 - (36%)

  Fly    50 QSILGPEVPAEWS-SPAKRECAECSCGNI-----------------------NTRHRIVGGQETE 90
            |.::..:...:|| ..:...|...|||.:                       |:.:.:||.:..|
Human  2631 QRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRE 2695

  Fly    91 VHEYPWMIMLMWFGN--------------FY-----------------CGA--SLVN-----DQY 117
            .     |...:|.|:              ||                 ||.  .:||     :.|
Human  2696 C-----MANGLWSGSEVRCLATQTKLHSIFYKLLFDVLSSPSLTKAGHCGTPEPIVNGHINGENY 2755

  Fly   118 ALTAA---HCVNGFYHRLI--TVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRF 177
            :...:   .|..||  |||  :||:.:   ||.|                :|.:.        .|
Human  2756 SYRGSVVYQCNAGF--RLIGMSVRICQ---QDHH----------------WSGKT--------PF 2791

  Fly   178 NEPVRLGIDMHPVCMPTPSENYAGQTAV--VTGWGALSEGGPISDTLQEVE----VPILSQEECR 236
            ..|:..|...:||...|....:.....|  |...|.::||...|..|...:    :|......|.
Human  2792 CVPITCGHPGNPVNGLTQGNQFNLNDVVKFVCNPGYMAEGAARSQCLASGQWSDMLPTCRIINCT 2856

  Fly   237 NSNYGESKI---------------TDNMIC-AGYVEQGGKD-SCQGDS----------------- 267
            :..:.|:.:               |.:..| .|:...|... |||||.
Human  2857 DPGHQENSVRQVHASGPHRFSFGTTVSYRCNHGFYLLGTPVLSCQGDGTWDRPRPQCLLVSCGHP 2921

  Fly   268 GGPMHVLGSGDAYQLAGIVSWGEGC-AKPNAPGVYTRV-GSFNDWIAENTRDACSCAQPEAAGEP 330
            |.|.|...|||:|.:..:|.:  .| .|....|..||: |....|  ..:...||.......|:|
Human  2922 GSPPHSQMSGDSYTVGAVVRY--SCIGKRTLVGNSTRMCGLDGHW--TGSLPHCSGTSVGVCGDP 2982

  Fly   331 ASPMETTEQGD 341
            ..|......||
Human  2983 GIPAHGIRLGD 2993

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	64/313 (20%)
		Tryp_SPc	83..314	CDD:238113	65/315 (21%)
CSMD2	NP_001268885.1	CUB	66..173	CDD:238001
		CCP	179..236	CDD:214478
		CUB	242..345	CDD:238001
		CCP	383..441	CDD:153056
		CUB	445..553	CDD:278839
		CCP	561..615	CDD:153056
		CUB	618..725	CDD:238001
		CCP	731..789	CDD:153056
		CUB	792..899	CDD:238001
		CCP	907..961	CDD:153056
		CUB	964..1072	CDD:238001
		CCP	1079..1135	CDD:153056
		CUB	1138..1245	CDD:238001
		CCP	1251..1308	CDD:153056
		CUB	1311..1419	CDD:238001
		CCP	1425..1482	CDD:153056
		CUB	1485..1590	CDD:278839
		CCP	<1595..>1687	CDD:332582
		CUB	1659..1766	CDD:238001
		CCP	1775..1833	CDD:153056
		CUB	1836..1941	CDD:238001
		CCP	1949..2005	CDD:153056
		CUB	2008..2115	CDD:238001
		Sushi	2121..2176	CDD:306569
		CUB	2180..2286	CDD:238001
		Sushi	2292..2349	CDD:306569
		CUB	2357..2463	CDD:238001
		CCP	<2486..2642	CDD:332582	1/10 (10%)
		CCP	2609..2850	CDD:332582	47/252 (19%)
		CCP	2792..3032	CDD:332582	46/206 (22%)
		Sushi	3037..3091	CDD:306569
		CCP	3091..3330	CDD:332582
		CCP	3290..>3389	CDD:332582

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910