DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and f7

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_571894.2	Gene:	f7 / 114423	ZFINID:	ZDB-GENE-010814-1	Length:	433	Species:	Danio rerio

Alignment Length:	250	Identity:	95/250 - (38%)
Similarity:	136/250 - (54%)	Gaps:	22/250 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 INTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGFYHRLITVRLLEHN 141
            ::.|.|||||.|......||.::|.:....:||..:....:.||||||:.....:.:.:...||:
Zfish   190 VDLRSRIVGGSECPKGHCPWQVLLKYGEKGFCGGVIYKPTWILTAAHCLEKLKVKFLRIVAGEHD 254

  Fly   142 RQDSHVKIVDR------RVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMP----TPS 196
            .:      ||.      :|.::..||.|.:...||||||:|...|:...:...|||:|    ...
Zfish   255 LE------VDEGTEQLIQVDQMFTHPAYVSETADSDIALLRLRTPIVYSVYAVPVCLPLREMAER 313

  Fly   197 ENYAGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEEC-RNSNYGESKITDNMICAGYVEQGGK 260
            |.:|.....|:|||..||.||.|..|:.:.||.:..:|| :.||.   .:|.||.||||:| |.:
Zfish   314 ELWAVSKHTVSGWGKRSEDGPTSRLLRRLLVPRIRTQECVQVSNL---TLTSNMFCAGYIE-GRQ 374

  Fly   261 DSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENT 315
            |||:||||||: |....|...|.||||||:|||:|.:.|:||||.::..||.:.|
Zfish   375 DSCKGDSGGPL-VTRYRDTAFLLGIVSWGKGCARPGSYGIYTRVSNYLQWIRQTT 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	91/239 (38%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	92/241 (38%)
f7	NP_571894.2	GLA	19..82	CDD:214503
		EGF_CA	86..121	CDD:238011
		FXa_inhibition	131..166	CDD:291342
		Tryp_SPc	195..424	CDD:214473	91/239 (38%)
		Tryp_SPc	196..427	CDD:238113	92/241 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910