DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and AgaP_AGAP013020

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_003435910.1	Gene:	AgaP_AGAP013020 / 11175979	VectorBaseID:	AGAP013020	Length:	454	Species:	Anopheles gambiae

Alignment Length:	326	Identity:	77/326 - (23%)
Similarity:	136/326 - (41%)	Gaps:	77/326 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 ATPSLRSASDPEKILNNLAQLRQSSFLDWIQSILGPEVPAEWSSPAKRECAECSCGNINTRHRIV 84
            :|.||.|.:|...:  |:.|.:.            |:.|.:...|.|           ...|..:
Mosquito   165 STQSLVSTNDGTNV--NVIQYQP------------PQTPVDCGLPDK-----------GFSHYSI 204

  Fly    85 GGQETEVHEYPWMIMLMWFGN-----FYCGASLVNDQYALTAAHCV---NGFYHRL--ITVRLLE 139
            .|.......:||...:...|:     :.||::::.:::.:||||||   :|....:  :||....
Mosquito   205 NGVHAHKGMFPWAAPIFHTGSSSKPRYICGSTILTERHLVTAAHCVYNSDGIKQNVSDLTVVPGM 269

  Fly   140 HNRQD-SHVKIVDRRVSRVLIHPKYSTRN---FDSDIALIRFNEPVRLGIDMHPVCMPTPSEN-- 198
            ||..: ....:.:|.|.::.:|..|...:   .|:|||::..::|:.....:.|:||.:.|:|
Mosquito   270 HNIDNFFEADLQERGVKKIFVHNDYFFEHGMLVDADIAVLLLDDPITYNKLVRPICMWSDSDNLE 334

  Fly   199 -YAGQTAVVTGWGALSEGGPISDTLQEVEVP------ILSQEECRNSNY-----GESKITDNMIC 251
             ..|....|:|||...:|        :.::|      ::.::.| |.|.     .:::|    .|
Mosquito   335 KIVGDEGFVSGWGVTEDG--------KAKIPSYVMATVVDRQTC-NRNLDRLFAAKARI----FC 386

  Fly   252 AGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGE------GCAKPNAPGVYTRVGSFNDW 310
            |   :..|...|.||||... |:..|..|.:.||||:|:      .||..... |||.:..|..|
Mosquito   387 A---DGHGSVPCTGDSGSGF-VIKRGPRYYIRGIVSFGQFDPKTLTCATDKYV-VYTDIAPFRYW 446

  Fly   311 I 311
            :
Mosquito   447 L 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	64/262 (24%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	65/263 (25%)
AgaP_AGAP013020	XP_003435910.1	GD_N	46..146	CDD:292649
		Tryp_SPc	204..450	CDD:238113	65/262 (25%)
		Tryp_SPc	204..446	CDD:214473	64/259 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910