Protein Alignment CG18735 and PRSS21

DIOPT Version :10

• Sequence 1: NP_652645.1
• Gene: CG18735 / 59137
• FlyBaseID: FBgn0042098
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 307
• Identity: 99/307 - (32%)
• Similarity: 144/307 - (46%)
• Gaps: 64/307 - (20%)

  Fly    64 PAKRECAECS--CGNINTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHC-- 124
            |..:|.|..|  ||......|||||::.|:..:||...|..:.:..||.||::.::|||||||
Human    21 PESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFE 85

  Fly   125 --------------------------VNGFYHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKY 163
                                      :..:|.|..                    ||.:.:.|:|
Human    86 TYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYF--------------------VSNIYLSPRY 130

  Fly   164 STRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENYAGQT-AVVTGWGALSEGG--PISDTLQEV 225
             ..|...||||::.:.||.....:.|:|:...:..:..:| ..|||||.:.|..  |...|||||
Human   131 -LGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEV 194

  Fly   226 EVPILSQEECRN--SNYGESK-ITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVS 287
            :|.|::...|.:  ..|...| |..:|:|||.. |||||:|.||||||:....:|..||: |:||
Human   195 QVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNA-QGGKDACFGDSGGPLACNKNGLWYQI-GVVS 257

  Fly   288 WGEGCAKPNAPGVYTRVGSFNDWIAENTRDACSCAQPEAAGEPASPM 334
            ||.||.:||.|||||.:....:|| :........:||    :|:.|:
Human   258 WGVGCGRPNRPGVYTNISHHFEWI-QKLMAQSGMSQP----DPSWPL 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	88/264 (33%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	88/264 (33%)