DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and si:dkey-32n7.7

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_021335883.1	Gene:	si:dkey-32n7.7 / 108191692	ZFINID:	ZDB-GENE-121214-179	Length:	609	Species:	Danio rerio

Alignment Length:	326	Identity:	114/326 - (34%)
Similarity:	157/326 - (48%)	Gaps:	55/326 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 VPAEW------SSPAKREC-------------AECSCGNINTRHRIVGGQETEVHEYPWMIMLMW 102
            |...|      ||..|..|             |.|....:|:.:..||||.:....:||...|.|
Zfish   263 VKGRWVFRVDNSSEVKGSCINTNSQALDSPSAAVCGIIPVNSSNGTVGGQNSSAVHWPWQASLYW 327

  Fly   103 FGNFYCGASLVNDQYALTAAHCV----NGFYHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKY 163
            :....||.||:|.::.|:||||.    ||||   :||.|....:.......:.|.|..|:.||.|
Zfish   328 YSGQTCGGSLINKEWVLSAAHCFNGQRNGFY---LTVILGPKTQNKYDPSRISRSVKAVIKHPYY 389

  Fly   164 STRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENYAGQT-AVVTGWGALSEGGPISD--TLQEV 225
            :....|:||||:|.:.|:.....:.|||:......:...| :.:|.|..:|:|.|:..  ..|||
Zfish   390 NPNTNDNDIALVRLSFPITFTDSIRPVCLAAEGSVFNSDTESWITTWRNISDGVPLPSPKIFQEV 454

  Fly   226 EVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGE 290
            |||::...:| |..||...|||||||||.::: |||.||||||||| |......:..:||||:|.
Zfish   455 EVPVIGNRQC-NCLYGVGSITDNMICAGLLKE-GKDLCQGDSGGPM-VSNQSSVWVQSGIVSFGS 516

  Fly   291 GCAKPNAPGVYTRVGSFNDWIAENTRDACSCAQPEAAGEPASPMETTEQGDQENTTANGAAEADP 355
            |||:...|||||||..:.:||   |...||        :|...::.|..|            |||
Zfish   517 GCAQSEFPGVYTRVSRYQEWI---TYFTCS--------DPPGFVQFTSTG------------ADP 558

  Fly   356 E 356
            :
Zfish   559 D 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	94/235 (40%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	96/237 (41%)
si:dkey-32n7.7	XP_021335883.1	NIDO	4..63	CDD:310601
		NIDO	141..272	CDD:322035	2/8 (25%)
		Tryp_SPc	309..537	CDD:238113	94/233 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587886
Domainoid	1	1.000	191	1.000	Domainoid score	I3175
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	201	1.000	Inparanoid score	I3731
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380103at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6349
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.900