DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and tmprss2.15

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_031752206.1	Gene:	tmprss2.15 / 101732233	XenbaseID:	XB-GENE-22065943	Length:	504	Species:	Xenopus tropicalis

Alignment Length:	258	Identity:	90/258 - (34%)
Similarity:	130/258 - (50%)	Gaps:	18/258 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 AECSCGN----------INTR--HRIVGGQETEVHEYPWMI-MLMWFGN--FYCGASLVNDQYAL 119
            |.|:.||          ::|:  .|||||....|.::||.: :|...|.  :.||.|::...:.:
Frog   240 ATCASGNMVSLRCISCGLSTKVDSRIVGGTPASVGDWPWQVELLKLVGTSIYLCGGSIITPHWIV 304

  Fly   120 TAAHCVNGFYHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLG 184
            ||||||.|........::...:............|.|.|:||.||:.....|:||::....:...
Frog   305 TAAHCVYGSTSTPSAFKVFAGSLTIQSYYSAGYTVERALVHPSYSSYTQIYDVALLKLTAALVFT 369

  Fly   185 IDMHPVCMPTPSENYA-GQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNYGESKITDN 248
            .::.|||:|.....:| ||...::|||..:|||.||..|....|||:|...|..:......|:..
Frog   370 TNLRPVCLPNVGMPWAEGQPCWISGWGTTAEGGSISKNLMAASVPIISSTTCNQAAVYGGAISST 434

  Fly   249 MICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWI 311
            |:||||: .||.|:||||||||: |..:...:.|.|..|||.|||:...||||..|..|.:||
Frog   435 MMCAGYL-SGGTDTCQGDSGGPL-VTKTNSLWWLVGDTSWGYGCARAYKPGVYGNVTVFIEWI 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	83/232 (36%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	84/233 (36%)
tmprss2.15	XP_031752206.1	LDLa	93..121	CDD:238060
		SRCR_2	164..259	CDD:406055	4/18 (22%)
		Tryp_SPc	265..498	CDD:238113	84/233 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910