DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and prss12

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_002934300.3	Gene:	prss12 / 100495119	XenbaseID:	XB-GENE-984837	Length:	851	Species:	Xenopus tropicalis

Alignment Length:	280	Identity:	94/280 - (33%)
Similarity:	133/280 - (47%)	Gaps:	45/280 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 AKRECAECSCGNINTRH----RIVGGQETEVHEYPWMIMLM-----WFGNFYCGASLVNDQYALT 120
            |.:|.:...||: ..:|    ||:||:.:....:||.:.|.     ..|...|||:|::..:.||
Frog   586 ANKELSPLVCGS-RLQHRRPKRIIGGKNSVRGGWPWQVALRLKSSHGDGRLLCGATLISSCWVLT 649

  Fly   121 AAHCVN-------------GFYHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDI 172
            ||||..             |.||.|:.....|           |..:.:::||..|.....|.||
Frog   650 AAHCFKRYGNNTRSYVIRVGDYHTLVPEEYEE-----------DMTIQQIIIHNDYRPDGNDYDI 703

  Fly   173 ALIRFN----EPVRLGIDMHPVCMPTPSE--NYAGQTAVVTGWGALSEGGPISDTLQEVEVPILS 231
            ||||.:    :.|:|...:.|.|:|...|  ........:||||  ..|...|.|||:..|.:|.
Frog   704 ALIRLHGTAEQCVQLSTHVLPACLPLRRERPQKTASNCYITGWG--DTGRAYSRTLQQATVTLLP 766

  Fly   232 QEECRNSNYGESKITDNMICAGYVE-QGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKP 295
            :..| ...| .|:.|..|:|||.|: |...||||||||||:....||.::.:.|:.|||.||...
Frog   767 KRVC-EERY-RSQFTGRMLCAGSVKTQKHVDSCQGDSGGPLVCERSGGSWIVYGVTSWGYGCGVK 829

  Fly   296 NAPGVYTRVGSFNDWIAENT 315
            ::|||||:|.:|..||...|
Frog   830 DSPGVYTKVSAFIPWIKSVT 849

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	86/253 (34%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	87/255 (34%)
prss12	XP_002934300.3	KR	78..140	CDD:412161
		SRCR	148..244	CDD:395421
		SR	257..356	CDD:214555
		SR	363..461	CDD:214555
		SR	476..575	CDD:214555
		Tryp_SPc	607..848	CDD:238113	87/255 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910