DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18735 and tmprss2.2

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_002941330.2	Gene:	tmprss2.2 / 100493729	XenbaseID:	XB-GENE-22065949	Length:	521	Species:	Xenopus tropicalis

Alignment Length:	253	Identity:	94/253 - (37%)
Similarity:	133/253 - (52%)	Gaps:	17/253 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 CAECSCGNINTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCV---NGFY- 129
            |..|.....:...|||||.......:.|.:.|.:.....||.|:::.::.:||||||   :||.
Frog   268 CISCGVSYNSVASRIVGGTYAAYGNWLWQVGLRYNTGILCGGSIISPKWIVTAAHCVYGTDGFLL 332

  Fly   130 ----HRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPV 190
                .|:....|...:..||...:|:    |::.||.|.|.:.|:||||:..:..:..|.:..||
Frog   333 SASGWRVFAGTLTLPSYYDSSGYLVE----RIIPHPGYKTSSNDNDIALMELSNGITFGYNTQPV 393

  Fly   191 CMPTPSENY-AGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNY-GESKITDNMICAG 253
            |:|.....: :|....::|||..|:||..|..||...|.::....| |.|| ...:||.:|||||
Frog   394 CLPNAGMFWSSGTPCWISGWGTTSQGGSASTYLQYAAVQLIDSNVC-NQNYVYNGQITASMICAG 457

  Fly   254 YVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWI 311
            |: .||.||||||||||: |..:...:.|.|..|||.|||:||.||||..:.||..||
Frog   458 YL-SGGVDSCQGDSGGPL-VTKTNGTWWLVGDTSWGYGCAQPNKPGVYGNMTSFLGWI 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	90/238 (38%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	91/239 (38%)
tmprss2.2	XP_002941330.2	LDLa	<111..134	CDD:238060
		LDLa	145..174	CDD:238060
		SRCR_2	179..274	CDD:292133	2/5 (40%)
		Tryp_SPc	281..513	CDD:214473	90/238 (38%)
		Tryp_SPc	282..513	CDD:238113	89/237 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000