DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and hgfac

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_002939269.3	Gene:	hgfac / 100485696	XenbaseID:	XB-GENE-940012	Length:	595	Species:	Xenopus tropicalis

Alignment Length:	259	Identity:	88/259 - (33%)
Similarity:	133/259 - (51%)	Gaps:	17/259 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 PAKRECAECSCGNINTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHC-VNG 127
            ||..:|.:.....:..|.||:||.......:|| :..::.||::|..||:...:.::|||| .:.
Frog   333 PAPPKCGKKHEKRVVARGRILGGNSALPGSHPW-VAGIYIGNYFCAGSLIQPCWVVSAAHCFADS 396

  Fly   128 FYHRLITVRLLEH--NRQDSHVKIVDRRVSRVLIHPKYST--RNFDSDIALIRF----NEPVRLG 184
            .....|.|.|.:|  |:.....:..:  |.|.:.:.|||.  || :.||.||:.    |...:..
Frog   397 PSKSKIRVVLGQHFFNQTTDVTQTFE--VERYIFYDKYSVFKRN-EHDIVLIKLKRINNACAKKT 458

  Fly   185 IDMHPVCMPTPSENYA-GQTAVVTGWGALSEGG-PISDTLQEVEVPILSQEECRNSNYGESKITD 247
            ..:..:|:|..|..:| .....:.|||.:.|.. ..:..|||..||::...:|.:.....::|::
Frog   459 QFVQTICLPDVSAPFADDHHCQIAGWGRMHEDSTEYAQNLQEAIVPLVPDNKCSSPEIYGAEISE 523

  Fly   248 NMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWI 311
            ||.||||.: ...||||||||||:.......:| |.|||||||||...|.|||||:|.::.|||
Frog   524 NMFCAGYFD-CTIDSCQGDSGGPLACEKDKISY-LWGIVSWGEGCGNHNKPGVYTKVSNYVDWI 585

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	82/239 (34%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	83/240 (35%)
hgfac	XP_002939269.3	FN2	52..98	CDD:238019
		EGF_CA	109..145	CDD:238011
		FN1	147..185	CDD:238018
		KR	235..319	CDD:294073
		Tryp_SPc	351..585	CDD:214473	82/239 (34%)
		Tryp_SPc	352..588	CDD:238113	83/240 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910