DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and LOC100331291

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_009295692.1	Gene:	LOC100331291 / 100331291	-ID:	-	Length:	932	Species:	Danio rerio

Alignment Length:	331	Identity:	115/331 - (34%)
Similarity:	162/331 - (48%)	Gaps:	78/331 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 CATPSLRSASDPEKILNNLAQLRQSSFLDWIQSILGPEVPAEWSSPAKRECAE------CSCG-N 76
            |:..|.:.||.  |.||.                :.||      ....::|.:      |.|| .
Zfish   644 CSPSSFKCASG--KCLNK----------------MNPE------CDGIKDCKDGSDELRCGCGTR 684

  Fly    77 INTRHRIVGGQETEVHEYPWMIMLMW--FGNFYCGASLVNDQYALTAAHCVNGFYHRLITVRLLE 139
            ...|.:||||.:.:...:||.:.|..  :|: .||||||..::.::||||.
Zfish   685 PRKRAKIVGGTDAQAGSWPWQVSLQMERYGH-VCGASLVASRWLVSAAHCF-------------- 734

  Fly   140 HNRQDSH-VKIVD----------------------RRVSRVLIHPKYSTRNFDSDIALIRFNEPV 181
               |||. :|..|                      |::.|:::|.:|.....|.||||:..:.||
Zfish   735 ---QDSDAIKYSDARSWRAYMGMRVMNSVSNAAATRQIRRIVLHSQYDQFTSDYDIALLELSAPV 796

  Fly   182 RLGIDMHPVCMPTPSENY-AGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNYGESKI 245
            .....:.|||:|.||..: :|.:..|||||.|:|.|.::..|||..|.|::...| |..|.:: :
Zfish   797 FFNELVQPVCVPAPSHVFTSGTSCFVTGWGVLTEEGELATLLQEATVNIINHNTC-NKMYDDA-V 859

  Fly   246 TDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDW 310
            |..|:|||.: |||.|:||||||||:..|..|..:.||||||||||||:.|.|||||||..|.||
Zfish   860 TPRMLCAGNI-QGGVDACQGDSGGPLVCLERGRRWFLAGIVSWGEGCARQNRPGVYTRVIKFTDW 923

  Fly   311 IAENTR 316
            |.:.|:
Zfish   924 IHQQTK 929

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	98/254 (39%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	100/256 (39%)
LOC100331291	XP_009295692.1	SEA	136..>220	CDD:307516
		CUB	315..415	CDD:238001
		CUB	421..528	CDD:238001
		LDLa	536..568	CDD:238060
		LDLa	606..636	CDD:238060
		LDLa	644..679	CDD:238060	10/58 (17%)
		Tryp_SPc	691..927	CDD:238113	100/256 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6379
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.810